Metal–Organic Framework Mediated Radio‐Enhancement Assessed in High‐Throughput‐Compatible 3D Tumor Spheroid Co‐Cultures
AL Neuer, A Vogel, A Gogos, VM Kissling… - Advanced …, 2023 - Wiley Online Library
Inorganic nanomaterials have gained increasing attention in radiation oncology, owing to
their radiation therapy enhancing properties. To accelerate candidate material selection and …
their radiation therapy enhancing properties. To accelerate candidate material selection and …
Cellular fate and performance of group IV metal organic framework radioenhancers
AL Neuer, A Jessernig, LRH Gerken, A Gogos… - Biomaterials …, 2022 - pubs.rsc.org
Nano-sized metal organic frameworks (nanoMOFs) have gained increasing importance in
biomedicine due to their tunable properties. In addition to their use as carriers in drug …
biomedicine due to their tunable properties. In addition to their use as carriers in drug …
Systemic immune effects boost radiotherapy
W Ngwa - Nature biomedical engineering, 2018 - nature.com
Systemic immune effects boost radiotherapy | Nature Biomedical Engineering Skip to main
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Co-delivery of PARP and PI3K inhibitors by nanoscale metal–organic frameworks for enhanced tumor chemoradiation
Due to their complementary activity, the use of DNA damage repair (DDR) inhibitors during
radiotherapy (RT) has yielded promising results. Unfortunately, this approach is often …
radiotherapy (RT) has yielded promising results. Unfortunately, this approach is often …
Interfering biosynthesis by nanoscale metal-organic frameworks for enhanced radiation therapy
Z Fu, Z Liu, J Wang, L Deng, H Wang, W Tang, D Ni - Biomaterials, 2023 - Elsevier
Radiation therapy (RT) is one of the most widely used cancer treatments. However, the
vigorous biosynthesis of cancer cells plays an important role for RT resistance. Herein, we …
vigorous biosynthesis of cancer cells plays an important role for RT resistance. Herein, we …
High‐Z Metal–Organic Frameworks for X‐ray Radiation‐Based Cancer Theranostics
MJ Neufeld, A Lutzke, G Pratx… - Chemistry–A European …, 2021 - Wiley Online Library
X‐ray radiation is commonly employed in clinical practice for diagnostic and therapeutic
applications. Over the past decade, developments in nanotechnology have led to the use of …
applications. Over the past decade, developments in nanotechnology have led to the use of …
Monte Carlo Simulation‐Guided Design of a Thorium‐Based Metal–Organic Framework for Efficient Radiotherapy‐Radiodynamic Therapy
High‐Z metal‐based nanoscale metal–organic frameworks (nMOFs) with photosensitizing
ligands can enhance radiation damage to tumors via a unique radiotherapy‐radiodynamic …
ligands can enhance radiation damage to tumors via a unique radiotherapy‐radiodynamic …
Multimodal Imaging-Guided Strategy for Developing 177Lu-Labeled Metal–Organic Framework Nanomedicine with Potential in Cancer Therapy
R Liang, F Li, X Chen, F Tan, T Lan… - … applied materials & …, 2023 - ACS Publications
Nano-metal–organic frameworks (nano-MOFs) labeled with radionuclides have shown great
potential in the anticancer field. In this work, we proposed to combine fluorescence imaging …
potential in the anticancer field. In this work, we proposed to combine fluorescence imaging …
Nanoscale metal-organic frameworks for x-ray activated in situ cancer vaccination
Cancer vaccines have been actively pursued to bolster antitumor immunity. Here, we
designed nanoscale metal-organic frameworks (nMOFs) as locally activable …
designed nanoscale metal-organic frameworks (nMOFs) as locally activable …
In Vivo Targeting and Positron Emission Tomography Imaging of Tumor with Intrinsically Radioactive Metal–Organic Frameworks Nanomaterials
D Chen, D Yang, CA Dougherty, W Lu, H Wu, X He… - ACS …, 2017 - ACS Publications
Nanoscale metal–organic frameworks (nMOF) materials represent an attractive tool for
various biomedical applications. Due to the chemical versatility, enormous porosity, and …
various biomedical applications. Due to the chemical versatility, enormous porosity, and …