Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with increased
prevalence and incidence in recent decades. Its etiology remains largely unclear, but it …

The valproic acid (VPA) animal model of autism spectrum disorder (ASD) is one of the most
widely used animal model in the field. Like any other disease models, it can't model the …

Autism is a neuro-developmental pathology affecting 1 out of 100 children worldwide. The
trauma and social consequences induced by autism are a real public health issue …

Despite the substantial progress made in identifying genetic defects in autism spectrum
disorder (ASD), the etiology for majority of ASD individuals remains elusive. Maternal …

Autism is a lifelong neurodevelopmental disorder characterized by impairments in social
communication and interaction and by repetitive patterns of behavior, interests and activities …

Valproic acid or valproate (VPA) is an anti-convulsant and mood stabiliser effective in
treating epilepsy and bipolar disorders. Although in adults VPA is well tolerated and safe …

Impairments in social interaction and verbal and non verbal communication are among the
main features of Autism Spectrum Disorder (ASD). The causes of ASD are still unknown but …

Despite the increasing prevalence of autism spectrum disorder (ASD), there is still a
deficiency in understanding its exact pathophysiology and treatment, therefore validation of …

Two recent epidemiological investigations in children exposed to valproic acid (VPA)
treatment in utero have reported a significant risk associated with neurodevelopmental …

Prenatal treatment with the antiepileptic drug valproic acid (VPA) is associated with a
significant risk of somatic anomalies, neurodevelopmental delays, and 7–10× increase in …