Tyrosine kinase inhibitors and pregnancy in chronic myeloid leukemia: opinion, evidence, and recommendations

E Abruzzese, M Mauro, J Apperley… - Therapeutic …, 2020 - journals.sagepub.com
With survival expectation that of age-matched controls and given excellent response and
worldwide access to tyrosine kinase inhibitors (TKI), family planning is increasingly …

Treatment of CML in pregnancy

HF Robertson, JF Apperley - Hematology, 2022 - ashpublications.org
Since the introduction of tyrosine kinase inhibitors (TKIs) at the beginning of the millennium,
the outlook for patients with chronic myeloid leukemia (CML) has improved remarkably. As …

Family planning and pregnancy in patients with chronic myeloid leukemia

E Berman - Current Hematologic Malignancy Reports, 2023 - Springer
Abstract Purpose of Review The goal of this review is to summarize what is known about
pregnancy in women with chronic myeloid leukemia (CML): there are very few guidelines …

Managing pregnancy in chronic myeloid leukemia

R Palani, D Milojkovic, JF Apperley - Chronic myeloid leukemia, 2016 - Springer
The success of tyrosine kinase inhibitors (TKIs) in the treatment of chronic myeloid
leukaemia (CML) has resulted in a return to a normal life expectancy for the majority of …

[HTML][HTML] Tyrosine kinase inhibitors and pregnancy

E Abruzzese, MM Trawinska, AP Perrotti… - … of Hematology and …, 2014 - ncbi.nlm.nih.gov
The management of patients with chronic myeloid leukemia (CML) during pregnancy has
become recently a matter of continuous debate. The introduction of the Tyrosine Kinase …

Management of pregnant chronic myeloid leukemia patients

E Abruzzese, MM Trawinska, P de Fabritiis… - Expert Review of …, 2016 - Taylor & Francis
Introduction: Since the introduction of tyrosine kinase inhibitors (TKIs) therapy, chronic
myeloid leukemia (CML), has moved from a fatal illness to a manageable disease with a …

Pregnancy: part of life in chronic myelogenous leukemia

AD Law, D Dong Hwan Kim, JH Lipton - Leukemia & Lymphoma, 2017 - Taylor & Francis
Management of pregnant patients with chronic myelogenous leukemia (CML) is challenging.
Some of the factors that need to be considered include stage of pregnancy, disease status …

[HTML][HTML] Pregnancy outcomes of women whom spouse fathered children after tyrosine kinase inhibitor therapy for chronic myeloid leukemia: A systematic review

Z Szakács, PJ Hegyi, N Farkas, P Hegyi, M Balaskó… - PLoS …, 2020 - journals.plos.org
Introduction The introduction of tyrosine kinase inhibitors (TKIs) has revolutionized the
therapy of chronic myeloid leukemia (CML). Although the efficacy of TKIs is beyond dispute …

Planned pregnancy in female patients with chronic myeloid leukemia receiving tyrosine kinase inhibitor therapy

X Dou, Y Qin, X Huang, Q Jiang - The Oncologist, 2019 - academic.oup.com
Background The aim of this study was to explore outcomes of planned pregnancy in female
patients with chronic myeloid leukemia (CML) on tyrosine kinase inhibitors (TKIs). Materials …

Management of chronic myeloid leukemia during pregnancy among patients treated with a tyrosine kinase inhibitor: a single-Center experience

R Assi, H Kantarjian, M Keating… - Leukemia & …, 2021 - Taylor & Francis
Tyrosine kinase inhibitors (TKIs) are teratogenic. Chronic myeloid leukemia (CML) is
increasingly identified in younger patients who wish to conceive, the management of CML …