Redox mechanisms in hepatic chronic wound healing and fibrogenesis

E Novo, M Parola - Fibrogenesis & tissue repair, 2008 - Springer
Reactive oxygen species (ROS) generated within cells or, more generally, in a tissue
environment, may easily turn into a source of cell and tissue injury. Aerobic organisms have …

Redox control of liver function in health and disease

M Mari, A Colell, A Morales, C von Montfort… - Antioxidants & redox …, 2010 - liebertpub.com
Reactive oxygen species (ROS), a heterogeneous population of biologically active
intermediates, are generated as by-products of the aerobic metabolism and exhibit a dual …

Targeting oxidative stress for the treatment of liver fibrosis

T Luangmonkong, S Suriguga, HAM Mutsaers… - Reviews of Physiology …, 2018 - Springer
Oxidative stress is a reflection of the imbalance between the production of reactive oxygen
species (ROS) and the scavenging capacity of the antioxidant system. Excessive ROS …

Role of hydrogen peroxide and oxidative stress in healing responses

M Rojkind, JA Dominguez-Rosales, N Nieto… - Cellular and Molecular …, 2002 - Springer
Oxidative stress is a host defense mechanism whose involvement in maintaining
homeostasis and/or inducing disease has been widely investigated over the past decade …

[HTML][HTML] Biochemical basis and metabolic interplay of redox regulation

L Zhang, X Wang, R Cueto, C Effi, Y Zhang, H Tan… - Redox biology, 2019 - Elsevier
Accumulated evidence strongly indicates that oxidative stress, characterized by an
imbalance between reactive oxygen species (ROS) production and antioxidants in favor of …

[图书][B] Liver pathophysiology: therapies and antioxidants

P Muriel - 2017 - books.google.com
Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology,
physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an …

[HTML][HTML] Role of oxidative stress in liver health and disease

P Muriel, KR Gordillo - Oxidative Medicine and Cellular Longevity, 2016 - ncbi.nlm.nih.gov
Liver diseases are a worldwide medical problem because the liver is the principal
detoxifying organ and maintains metabolic homeostasis. The liver metabolizes various …

Role of oxidative stress and molecular changes in liver fibrosis: a review

V Sánchez-Valle, NC Chavez-Tapia… - Current medicinal …, 2012 - ingentaconnect.com
Liver fibrosis represents a health problem with significant morbidity and mortality that affects
100 million people worldwide. It is a final pathway to several chronic liver diseases and is …

Cellular redox homeostasis

K Le Gal, EE Schmidt, VI Sayin - Antioxidants, 2021 - mdpi.com
Cellular redox homeostasis is an essential and dynamic process that ensures the balance
between reducing and oxidizing reactions within cells and regulates a plethora of biological …

Nitric oxide and redox regulation in the liver: part II. Redox biology in pathologic hepatocytes and implications for intervention

DL Diesen, PC Kuo - Journal of Surgical Research, 2011 - Elsevier
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are created in normal
hepatocytes and are critical for normal physiologic processes, including oxidative …