Effects of 17 α-methyltestosterone on the transcriptome, gonadal histology and sex steroid hormones in Pseudorasbora parva

J Wang, J Zhou, Q Yang, W Wang, Q Liu, W Liu, S Liu - Theriogenology, 2020 - Elsevier
In recent years, the increasing use of environmental endocrine disruptors has caused
serious environmental pollution and hurt aquatic organisms. It is still risky for aquatic species …

Effects of 17 α-methyltestosterone on transcriptome, gonadal histology and sex steroid hormones in rare minnow Gobiocypris rarus

J Gao, S Liu, Y Zhang, Y Yang, C Yuan, S Chen… - … and Physiology Part D …, 2015 - Elsevier
Abstract The 17α-methyltestosterone (MT), a synthetic androgen, is known for its
interference effects on the endocrine system. Aiming to investigate the transcriptome …

The effects of 17α‐methyltestosterone on gonadal histology and gene expression along hypothalamic‐pituitary‐gonadal axis, germ cells, sex determination, and …

M Li, N Zhang, Y Huang, CG Pan, Z Dong… - Environmental …, 2024 - Wiley Online Library
As a synthetic androgen, 17α‐methyltestosterone (MT) is widely used in aquaculture to
induce sex reversal and may pose a potential risk to aquatic organisms. This ecological risk …

[HTML][HTML] Effects of 17α-Methyltestosterone on the Transcriptome and Sex Hormones in the Brain of Gobiocypris rarus

S Liu, Y Chen, T Li, L Qiao, Q Yang, W Rong… - International Journal of …, 2023 - mdpi.com
17α-Methyltestosterone (MT), a synthetic environmental endocrine disruptor with androgenic
effects, has been shown to disrupt the reproductive system and inhibit germ cell maturation …

[HTML][HTML] Pituitary transcriptome analysis of mandarin fish (Siniperca chuatsi) reveals dietary 17α-methyltestosterone disturbs hypothalamic-pituitary-gonadal axis by …

C Han, S Liu, K Chen, S Zhong, M Li, Y Jiang… - Aquaculture …, 2024 - Elsevier
Abstract 17α-methyltestosterone (MT), as a synthetic androgen, has been widely used in
medicine and aquaculture industry. However, the related molecular regulating mechanism …

Molecular and Physiological Effects of 17α-methyltestosterone on Sex Differentiation of Black Rockfish, Sebastes schlegelii

H Huang, Y Liu, Q Wang, C Dong, L Dong, J Zhang… - Genes, 2024 - mdpi.com
It is widely known that all-female fish production holds economic value for aquaculture.
Sebastes schlegelii, a preeminent economic species, exhibits a sex dimorphism, with …

[HTML][HTML] Comparative Analysis of miRNA-mRNA Regulation in the Testes of Gobiocypris rarus following 17α-Methyltestosterone Exposure

S Liu, J Zhou, Q Yang, Y Chen, Q Liu, W Wang… - International Journal of …, 2023 - mdpi.com
17α-Methyltestosterone (17MT), a synthetic organic compound commonly found in sewage
waters, can affect reproduction in aquatic animals, such as tilapia and yellow catfish. In the …

Molecular mechanism of endocrine system impairment by 17α-methyltestosterone in gynogenic Pengze crucian carp offspring

Y Zheng, J Chen, Y Liu, J Gao, Y Yang, Y Zhang… - Ecotoxicology and …, 2016 - Elsevier
The effects of synthetic androgen 17α-methyltestosterone (MT) on endocrine impairment
were examined in crucian carp. Immature 7-month old mono-female Pengze crucian carp …

Transcriptomics profiling and steroid production in mummichog (Fundulus heteroclitus) testes after treatment with 5α-dihydrotestosterone

A Feswick, JS Ings, MA Doyle, T Bosker… - General and …, 2014 - Elsevier
Abstract 5α-Dihydrotestosterone (DHT) is a potent androgen in mammals with multiple roles;
however the physiological actions of DHT in male fishes are not well known. To address this …

Time‐Dependent transcriptional profiles of genes of the hypothalamic‐pituitary‐gonadal axis in medaka (Oryzias latipes) exposed to fadrozole and 17β‐trenbolone

X Zhang, M Hecker, JW Park… - … and Chemistry: An …, 2008 - Wiley Online Library
Both the anabolic androgen 17β‐trenbolone (TRB) and the aromatase inhibitor fadrozole
(FAD) can cause decreased plasma concentrations of estrogen (E2) and reduce fecundity of …