Dendritic cell subsets in cancer immunity and tumor antigen sensing
Dendritic cells (DCs) exhibit a specialized antigen-presenting function and play crucial roles
in both innate and adaptive immune responses. Due to their ability to cross-present tumor …
in both innate and adaptive immune responses. Due to their ability to cross-present tumor …
Dendritic cells and cancer: from biology to therapeutic intervention
Inducing effective anti-tumor immunity has become a major therapeutic strategy against
cancer. Dendritic cells (DC) are a heterogenous population of antigen presenting cells that …
cancer. Dendritic cells (DC) are a heterogenous population of antigen presenting cells that …
Molecular mechanisms involved in dendritic cell dysfunction in cancer
M Tang, J Diao, MS Cattral - Cellular and Molecular Life Sciences, 2017 - Springer
Dendritic cells (DC) play a pivotal role in the tumor microenvironment (TME). As the primary
antigen-presenting cells in the tumor, DCs modulate anti-tumor responses by regulating the …
antigen-presenting cells in the tumor, DCs modulate anti-tumor responses by regulating the …
[HTML][HTML] Tumor-infiltrating dendritic cell states are conserved across solid human cancers
GM Gerhard, R Bill, M Messemaker, AM Klein… - Journal of Experimental …, 2021 - rupress.org
Dendritic cells (DCs) contribute a small fraction of the tumor microenvironment but are
emerging as an essential antitumor component based on their ability to foster T cell …
emerging as an essential antitumor component based on their ability to foster T cell …
Once upon a prime: DCs shape cancer immunity
M Zagorulya, S Spranger - Trends in cancer, 2023 - cell.com
Cytotoxic CD8+ T cells are potent killers of diseased cells, but their functional capacity is
often compromised in cancer. The quality of antitumor T cell immunity is determined during T …
often compromised in cancer. The quality of antitumor T cell immunity is determined during T …
Insights into dendritic cells in cancer immunotherapy: from bench to clinical applications
A Salah, H Wang, Y Li, M Ji, WB Ou, N Qi… - Frontiers in Cell and …, 2021 - frontiersin.org
Dendritic cells (DCs) are efficient antigen-presenting cells (APCs) and potent activators of
naïve T cells. Therefore, they act as a connective ring between innate and adaptive …
naïve T cells. Therefore, they act as a connective ring between innate and adaptive …
Dendritic cells and CD8 T cell immunity in tumor microenvironment
C Fu, A Jiang - Frontiers in immunology, 2018 - frontiersin.org
Dendritic cells (DCs) play a central role in the regulation of the balance between CD8 T cell
immunity vs. tolerance to tumor antigens. Cross-priming, a process which DCs activate CD8 …
immunity vs. tolerance to tumor antigens. Cross-priming, a process which DCs activate CD8 …
The role of dendritic cells in cancer and anti-tumor immunity
AE Marciscano, N Anandasabapathy - Seminars in immunology, 2021 - Elsevier
Dendritic cells (DC) are key sentinels of the host immune response with an important role in
linking innate and adaptive immunity and maintaining tolerance. There is increasing …
linking innate and adaptive immunity and maintaining tolerance. There is increasing …
[HTML][HTML] The role of dendritic cells in tumor microenvironments and their uses as therapeutic targets
Dendritic cells (DC), which consist of several different subsets, specialize in antigen
presentation and are critical for mediating the innate and adaptive immune responses. DC …
presentation and are critical for mediating the innate and adaptive immune responses. DC …
Tumor-altered dendritic cell function: implications for anti-tumor immunity
KM Hargadon - Frontiers in immunology, 2013 - frontiersin.org
Dendritic cells (DC) are key regulators of both innate and adaptive immunity, and the array
of immunoregulatory functions exhibited by these cells is dictated by their differentiation …
of immunoregulatory functions exhibited by these cells is dictated by their differentiation …