Traumatic brain injury (TBI) caused by acoustic blast overpressure (ABO) is frequently
associated with chronic visual deficits in military personnel and civilians. In this study, we …

Acoustic blast overpressure (ABO) injury in military personnel and civilians is often
accompanied by delayed visual deficits. However, most animal model studies dealing with …

Methods.: Healthy adult mice were exposed to an overpressure blast wave using a custom-
built blast chamber. The effects of blast exposure on retina and optic nerve function and …

Traumatic brain injury due to blast exposure is currently the most prevalent of war injuries.
Although secondary ocular blast injuries due to flying debris are more common, primary …

Traumatic brain injuries (TBI) of varied types are common across all populations and can
cause visual problems. For military personnel in combat settings, injuries from blast …

Indirect traumatic optic neuropathy (ITON) is a condition that is often associated with
traumatic brain injury and can result in significant vision loss due to degeneration of retinal …

Purpose A hallmark of retinal gliosis is the increased detection and modification of the type
III intermediate filament (IF) proteins vimentin and glial fibrillary acidic protein (GFAP). Here …

Blast has been the leading cause of injury, particularly traumatic brain injury and visual
system injury, in combat operations in Iraq and Afghanistan. We determined the effect of …

Purpose: In a mouse model of blast-mediated traumatic brain injury (bTBI), interleukin-1 (IL-
1)-pathway components were tested as potential therapeutic targets for bTBI-mediated …

Background Visual prognosis after an open globe injury is typically worse than after a closed
globe injury due, in part, to the immune response that ensues following open globe trauma …