Ethnopharmacological relevance Chronic intermittent hypoxia (CIH) is the primary
pathophysiological process of obstructive sleep apnea (OSA) and is closely linked to …

The current study tested the potential neuroprotective function of Tanshinone IIA (ThIIA) in
neuronal cells with oxygen-glucose deprivation (ODG) and re-oxygenation (OGDR). In SH …

Background: Tanshinone IIA is a key active ingredient of danshen, which is derived from the
dried root or rhizome of Salviae miltiorrhizae Bge. The tanshinone IIA has protective effects …

Sleep deprivation is commonplace in modern society, Short periods of continuous sleep
deprivation (SD) may negatively affect brain and behavioral function and may lead to vehicle …

Neonatal hypoxia-ischemia is one of the main reasons that cause neuronal damage and
neonatal death. Several studies have shown that tanshinone I (TsI), one of the major …

Traumatic brain injury (TBI) is a major source of mortality and long‐term disability worldwide.
The mechanisms associated with TBI development are poorly understood, and little …

Subarachnoid hemorrhage (SAH) is a fatal cerebrovascular condition with complex
pathophysiology that reduces brain perfusion and causes cerebral functional impairments …

Oxidative stress in retinal pigment epithelium (RPE) is considered to be a major contributor
to the development and progression of age-related macular degeneration (AMD). Previous …

Aims: Spinal cord injury (SCI) is a damage of spinal cord caused by trauma or diseases.
Here, we explored the effects of tanshinone IIA (Tan IIA) on SCI oxidative damage in vitro …

Hypoxic ischemic encephalopathy (HIE) is the most common brain injury following hypoxia
and/or ischemia caused by various factors during the perinatal period, resulting in …