Circulating 16S RNA in biofluids: extracellular vesicles as mirrors of human microbiome?

V Ricci, D Carcione, S Messina, GI Colombo… - International Journal of …, 2020 - mdpi.com
The human body is inhabited by around 1013 microbes composing a multicomplex system,
termed microbiota, which is strongly involved in the regulation and maintenance of …

A new horizon of precision medicine: combination of the microbiome and extracellular vesicles

J Yang, TS Shin, JS Kim, YK Jee, YK Kim - Experimental & molecular …, 2022 - nature.com
Over several decades, the disease pattern of intractable disease has changed from acute
infection to chronic disease accompanied by immune and metabolic dysfunction. In addition …

[HTML][HTML] Multicenter quality assessment of 16S ribosomal DNA-sequencing for microbiome analyses reveals high inter-center variability

A Hiergeist, U Reischl, A Gessner - International Journal of Medical …, 2016 - Elsevier
The composition of human as well as animal microbiota has increasingly gained in interest
since metabolites and structural components of endogenous microorganisms fundamentally …

Microbe-host communication by small RNAs in extracellular vesicles: vehicles for transkingdom RNA transportation

HJ Lee - International journal of molecular sciences, 2019 - mdpi.com
Extracellular vesicles (EVs) are evolutionary well-conserved nano-sized membranous
vesicles that are secreted by both prokaryotic and eukaryotic cells. Recently, they have …

Microbiota-derived extracellular vesicles detected in human blood from healthy donors

B Schaack, T Hindré, N Quansah, D Hannani… - International Journal of …, 2022 - mdpi.com
The microbiota constitutes an important part of the holobiont in which extracellular vesicles
(EVs) are key players in health, especially regarding inter-and intra-kingdom …

Unveiling the human gastrointestinal tract microbiome: the past, present, and future of metagenomics

K Athanasopoulou, PG Adamopoulos, A Scorilas - Biomedicines, 2023 - mdpi.com
Over 1014 symbiotic microorganisms are present in a healthy human body and are
responsible for the synthesis of vital vitamins and amino acids, mediating cellular pathways …

Bacterial extracellular vesicles in biofluids as potential diagnostic biomarkers

KY Su, JY Koh Kok, YW Chua, SD Ong… - Expert Review of …, 2022 - Taylor & Francis
ABSTRACT Introduction Extracellular vesicles (EVs) are spherical membrane-derived lipid
bilayers released by cells. The human microbiota consists of trillions of microorganisms, with …

Sequencing the human microbiome in health and disease

MJ Cox, WOCM Cookson… - Human molecular …, 2013 - academic.oup.com
Molecular techniques have revolutionized the practice of standard microbiology. In
particular, 16S rRNA sequencing, whole microbial genome sequencing and metagenomics …

Metagenomics of human microbiome: beyond 16s rDNA

MJ Gosalbes, JJ Abellan, A Durban… - Clinical Microbiology …, 2012 - Wiley Online Library
Clin Microbiol Infect 2012; 18 (Suppl. 4): 47–49 Abstract The gut microbiota presents a
symbiotic relationship with the human host playing a beneficial role in human health. Since …

Multi-method characterization of the human circulating microbiome

E Whittle, MO Leonard, R Harrison, TW Gant… - Frontiers in …, 2019 - frontiersin.org
The term microbiome describes the genetic material encoding the various microbial
populations that inhabit our body. Whilst colonization of various body niches (eg, the gut) by …