[HTML][HTML] Which adverse effects influence the dropout rate in selective serotonin reuptake inhibitor (SSRI) treatment? Results for 50,824 patients

K Kostev, J Rex, T Eith, C Heilmaier - GMS German Medical …, 2014 - ncbi.nlm.nih.gov
Background: Nowadays, selective serotonin reuptake inhibitors (SSRIs) are the most
frequently prescribed antidepressants due to their superior clinical efficacy, effectiveness …

Discontinuation symptoms in users of selective serotonin reuptake inhibitors in clinical practice: tapering versus abrupt discontinuation

ECG Van Geffen, JG Hugtenburg, ER Heerdink… - European journal of …, 2005 - Springer
Objective Tapering of selective serotonin reuptake inhibitor (SSRI) therapy, as opposed to
abrupt discontinuation, has been recommended by several guidelines and in the literature in …

Drop-out rates in placebo-controlled trials of antidepressant drugs: A systematic review and meta-analysis based on clinical study reports

T Sharma, LS Guski, N Freund… - … Journal of Risk & …, 2019 - content.iospress.com
OBJECTIVE: To study the drop-out rates in trials of selective serotonin and serotonin-
norepinephrine reuptake inhibitors (SSRIs and SNRIs). METHODS: This study is a …

Problems associated with long-term treatment with selective serotonin reuptake inhibitors

C Moret, M Isaac, M Briley - Journal of Psychopharmacology, 2009 - journals.sagepub.com
Although the selective serotonin reuptake inhibitors (SSRIs), which are now widely used as
a first-line treatment for depression and many other psychiatric conditions, are generally well …

Selective serotonin reuptake inhibitors: how long is long enough?

RP Thom, JL Alexander, D Baron… - Journal of Psychiatric …, 2021 - journals.lww.com
Selective serotonin reuptake inhibitors (SSRIs) are among the most commonly prescribed
medications. They are among the first-line medications for several chronic or relapsing …

Efficacy of selective serotonin reuptake inhibitors and adverse events: meta-regression and mediation analysis of placebo-controlled trials

M Barth, L Kriston, S Klostermann, C Barbui… - The British Journal of …, 2016 - cambridge.org
BackgroundIt has been suggested that the efficacy of antidepressants has been
overestimated in clinical trials owing to unblinding of drug treatments by adverse events …

What happens with adverse events during 6 months of treatment with selective serotonin reuptake inhibitors?

K Demyttenaere, A Albert, P Mesters… - Journal of Clinical …, 2005 - psychiatrist.com
Objective: Although adverse events are a key factor in compliance, their evolution during
treatment with antidepressants is poorly documented. Therefore, the time course of adverse …

Discontinuation syndromes with selective serotonin reuptake inhibitors: are there clinically relevant differences?

JS Olver, GD Burrows, TR Norman - CNS drugs, 1999 - Springer
Abstract Selective serotonin (5-hydroxytryptamine; 5-HT) reuptake inhibitors (SSRIs), like the
tricyclic antidepressants and monoamine oxidase inhibitors, are associated with a well …

Adverse reactions of selective serotonin reuptake inhibitors: reports from a spontaneous reporting system

O Spigset - Drug safety, 1999 - Springer
Objective The selective serotonin (5-hydroxytryptamine; 5-HT) reuptake inhibitors (SSRIs)
are extensively used in the treatment of depression, panic disorder and obsessive …

Low SSRI dosing in clinical practice—a register‐based longitudinal study

A Lisinski, F Hieronymus, E Eriksson… - Acta Psychiatrica …, 2021 - Wiley Online Library
Objective Since several recent meta‐analyses report a dose‐response relationship for the
antidepressant effect of the selective serotonin reuptake inhibitors (SSRIs), we investigated …