Purpose Computational modelling may improve the fundamental understanding of various
mechanisms of diseases more particularly related to clinical challenges. In this study the …

The relationship between infarct mechanics and ventricular function of the septal wall in the
presence of fibrotic infarct in the free wall remains poorly understood. This study compares …

The effect of myocardial infarction on the global functioning of the heart is well known. Less
is understood regarding the effect of LV fibrotic infarction on the cardiac mechanics of the …

The interventricular septum is the structure that separates the left and right ventricles of the
heart. Under normal loading conditions, it is concave to the left ventricle, but under abnormal …

The interventricular septum contributes to the pumping function of both ventricles. However,
unlike the ventricular wall, its mechanical behavior remains largely unknown. To fill the …

Identifying ventricle material properties and its infarct area after heart attack noninvasively is
of great important in clinical applications. An echo-based computational modeling approach …

Biomedical research has enjoyed an eruption of reductionism where organs are reduced to
their respective tissues, cells, and molecules. Although reductionism (including proteomic …

Mathematical modelling in biomechanics of infarcted left ventricle (LV) serves as an
indispensable tool for remodelling mechanism exploration, LV biomechanical property …

The physiological basis of the right ventricle diastolic function is not well studied. In most
heart failure, heart transplantation remains the first choice with survival ranges between 40 …

The shortening of the myocardial fibers is the microstructural engine that produces the
contraction of the cardiac muscle. The complex interplay between fibers shortening and …