[HTML][HTML] Restoring nervous system structure and function using tissue engineered living scaffolds
LA Struzyna, JP Harris, KS Katiyar… - Neural regeneration …, 2015 - journals.lww.com
Neural tissue engineering is premised on the integration of engineered living tissue with the
host nervous system to directly restore lost function or to augment regenerative capacity …
host nervous system to directly restore lost function or to augment regenerative capacity …
Neural tissue engineering for neuroregeneration and biohybridized interface microsystems in vivo (Part 2)
Neural tissue engineering offers tremendous promise to combat the effects of disease,
aging, or injury in the nervous system. Here we review neural tissue engineering with …
aging, or injury in the nervous system. Here we review neural tissue engineering with …
Living scaffolds for neuroregeneration
Neural tissue engineers are exploiting key mechanisms responsible for neural cell migration
and axonal pathfinding during embryonic development to create living scaffolds for …
and axonal pathfinding during embryonic development to create living scaffolds for …
Tissue-engineering approaches for axonal guidance
N Zhang, H Yan, X Wen - Brain Research Reviews, 2005 - Elsevier
Owing to the profound impact of nervous system damage, extensive studies have been
carried out aimed at facilitating axonal regeneration following injury. Tissue engineering, as …
carried out aimed at facilitating axonal regeneration following injury. Tissue engineering, as …
Neural tissue engineering: From bioactive scaffolds and in situ monitoring to regeneration
B Gong, X Zhang, AA Zahrani, W Gao, G Ma… - …, 2022 - Wiley Online Library
Peripheral nerve injury is a large‐scale problem that annually affects more than several
millions of people all over the world. It remains a great challenge to effectively repair nerve …
millions of people all over the world. It remains a great challenge to effectively repair nerve …
[HTML][HTML] Bundled three-dimensional human axon tracts derived from brain organoids
DK Cullen, WJ Gordián-Vélez, LA Struzyna… - Iscience, 2019 - cell.com
Reestablishing cerebral connectivity is a critical part of restoring neuronal network integrity
and brain function after trauma, stroke, and neurodegenerative diseases. Creating …
and brain function after trauma, stroke, and neurodegenerative diseases. Creating …
[HTML][HTML] Scaffolds with anisotropic structure for neural tissue engineering
Y Hu, H Zhang, H Wei, H Cheng, J Cai, X Chen… - Engineered …, 2022 - Elsevier
Nervous system injuries remain a great challenge due to limited natural tissue regeneration
capabilities. Neural tissue engineering has been regarded as a promising approach for …
capabilities. Neural tissue engineering has been regarded as a promising approach for …
Microtissue engineered constructs with living axons for targeted nervous system reconstruction
DK Cullen, MD Tang-Schomer, LA Struzyna… - … Engineering Part A, 2012 - liebertpub.com
As a common feature of many neurological diseases and injury, the loss of axon pathways
can have devastating effects on function. Here, we demonstrate a new strategy to restore …
can have devastating effects on function. Here, we demonstrate a new strategy to restore …
[HTML][HTML] Anatomically inspired three-dimensional micro-tissue engineered neural networks for nervous system reconstruction, modulation, and modeling
LA Struzyna, DO Adewole… - Journal of Visualized …, 2017 - ncbi.nlm.nih.gov
Functional recovery rarely occurs following injury or disease-induced degeneration within
the central nervous system (CNS) due to the inhibitory environment and the limited capacity …
the central nervous system (CNS) due to the inhibitory environment and the limited capacity …
Transplantable living scaffolds comprised of micro-tissue engineered aligned astrocyte networks to facilitate central nervous system regeneration
Neurotrauma, stroke, and neurodegenerative disease may result in widespread loss of
neural cells as well as the complex interconnectivity necessary for proper central nervous …
neural cells as well as the complex interconnectivity necessary for proper central nervous …