Sex differences in renin-angiotensin-aldosterone system affect extracellular volume in healthy subjects

TJ Toering, CM Gant, FW Visser… - American Journal …, 2018 - journals.physiology.org
Several studies reported sex differences in aldosterone. It is unknown whether these
differences are associated with differences in volume regulation. Therefore we studied both …

Disordered aldosterone-volume relationship in end-stage kidney disease

AS Bomback, AV Kshirsagar… - Journal of the renin …, 2009 - journals.sagepub.com
Introduction. Sodium loading, and subsequent volume expansion, suppresses aldosterone
levels in individuals with normal renal function. We hypothesised that loss of renal function …

Biological sex modulates the adrenal and blood pressure responses to angiotensin II

MZ Shukri, JW Tan, W Manosroi, LH Pojoga… - …, 2018 - Am Heart Assoc
The relationship between biological sex and aldosterone on blood pressure (BP) is unclear.
We hypothesized that sex would modify the interaction between aldosterone and vascular …

Body mass index predicts 24-hour urinary aldosterone levels in patients with resistant hypertension

T Dudenbostel, L Ghazi, M Liu, P Li, S Oparil… - …, 2016 - Am Heart Assoc
Prospective studies indicate that hyperaldosteronism is found in 20% of patients with
resistant hypertension. A small number of observational studies in normotensive and …

Hyperaldosteronism and hypertension: ethnic differences

CE Grim, AW Cowley Jr, P Hamet, D Gaudet… - …, 2005 - Am Heart Assoc
The purpose of this study is to evaluate the relationship between aldosterone and blood
pressure in a total of 220 normotensive and 293 essential hypertensive subjects in 2 …

Estrogens contribute to a sex difference in plasma potassium concentration: a mechanism for regulation of adrenal angiotensin receptors

W Zheng, M Shi, SE You, H Ji, DM Roesch - Gender medicine, 2006 - Elsevier
BACKGROUND:: The adrenal mineralocorticoid aldosterone promotes sodium (Na+)
reabsorption and potassium (K+) loss from the kidney. Female sex steroids such as estrogen …

Inadequate suppression of angiotensin II modulates left ventricular structure in humans.

MP Schlaich, HP Schobel, MR Langenfeld… - Clinical …, 1998 - europepmc.org
Background In a previous study we found that high angiotensin II levels in relation to the
corresponding urinary sodium excretion aggravate left ventricular hypertrophy in …

In water deprivation, osmolality becomes an important determinant of aldosterone secretion

EG Schneider - Physiology, 1990 - journals.physiology.org
The adrenal gland secretion of aldosterone is closely linked to the volume and composition
of the plasma compartment via the renin-angiotensin II system. In contrast, alterations in the …

Associations between circulating components of the renin-angiotensin-aldosterone system and left ventricular mass.

H Schunkert, HW Hense, M Muscholl, A Luchner… - Heart, 1997 - heart.bmj.com
OBJECTIVE: Cardiac growth may be modulated in part by the trophic effects of
neurohormones. The aim of the present study was to investigate the relation between the …

Suppression of plasma renin and plasma aldosterone during water immersion in normal man

M Epstein, DS Pins, J Sancho… - The Journal of Clinical …, 1975 - academic.oup.com
Previous studies from this laboratory have demonstrated that the redistribution of blood
volume and concomitant relative central hypervolemia induced by water immersion to the …