Atherosclerosis is an inflammatory disease of the large arteries that is the major cause of
cardiovascular disease (CVD) and stroke. Here, we review the current understanding of the …

Emerging evidence has spurred a considerable evolution of concepts relating to
atherosclerosis, and has called into question many previous notions. Here I review this …

The resolution of inflammation (or inflammation-resolution) is an active and highly
coordinated process. Inflammation-resolution is governed by several endogenous factors …

Despite the multifactorial nature of atherosclerosis, substantial evidence has established
inflammation as an often surreptitious, yet critical and unifying driving force which promotes …

A considerable volume of research over the last decade has focused on understanding the
fundamental mechanisms for the progression of atherosclerosis—the underlying cause for …

Atherosclerosis can be regarded as a chronic inflammatory state, in which macrophages
play different and important roles. Phagocytic proinflammatory cells populate growing …

After activation, cells of the myeloid lineage undergo robust metabolic transitions, as well as
discrete epigenetic changes, that can dictate both ongoing and future inflammatory …

Atherosclerosis occurs in the subendothelial space (intima) of medium-sized arteries at
regions of disturbed blood flow and is triggered by an interplay between endothelial …

Atherosclerosis is a chronic inflammatory vascular disease driven by traditional and
nontraditional risk factors. Genome-wide association combined with clonal lineage tracing …

Macrophages are becoming increasingly recognized as key agents in chronic diseases of
aging, including cancer, metabolic disease, and, the topic of this review, atherosclerosis. In …