Principal medium spiny projection neurons (MSNs) of the striatum have long been thought to
be homogeneous in their somatodendritic morphology and physiology. Recent work using …

The major afferent innervation of the basal ganglia is derived from the cortex and the
thalamus. These excitatory inputs mainly target the striatum where they innervate the …

The loss of striatal dopamine (DA) in Parkinson's disease (PD) models triggers a cell-type-
specific reduction in the density of dendritic spines in D2 receptor-expressing striatopallidal …

Dopaminergic modulation produces a variety of functional changes in the principal cell of
the striatum, the medium spiny neuron (MSN). Using a 189-compartment computational …

Medium spiny neurons (MSNs) constitute the vast majority of striatal neurons and the
principal interface between dopamine reward signals and functionally diverse cortico-basal …

The striatum projection neurons are striatonigral and striatopallidal medium-sized spiny
neurons (MSNs) that preferentially express D1 (D1R) and D2 (D2R) dopamine receptors …

The striatum receives major excitatory inputs from the cortex and thalamus that
predominantly target the spines of medium-sized spiny neurons (MSNs). We aimed to …

The principal neurons of the striatum, GABAergic medium spiny neurons (MSNs), are
interconnected by local recurrent axon collateral synapses. Although critical to many striatal …

Intracellular injection of HRP combined with immunocytochemistry for [Leu] enkephalin was
used to demonstrate striatal spiny neuron dendritic and local axonal arborizations in the …

D1 and D2 receptor expressing striatal medium spiny neurons (MSNs) are ascribed to
striatonigral (“direct”) and striatopallidal (“indirect”) pathways, respectively, that are believed …