Placental function in maternal obesity
Maternal obesity is associated with pregnancy complications and increases the risk for the
infant to develop obesity, diabetes and cardiovascular disease later in life. However, the …
infant to develop obesity, diabetes and cardiovascular disease later in life. However, the …
[HTML][HTML] Effects of maternal obesity on placental function and fetal development
Obesity has reached epidemic proportions and pregnancies in obese mothers have
increased risk for complications including gestational diabetes, hypertensive disorders …
increased risk for complications including gestational diabetes, hypertensive disorders …
Maternal pre-pregnancy obesity is associated with altered placental transcriptome
Maternal obesity has a major impact on pregnancy outcomes. There is growing evidence
that maternal obesity has a negative influence on placental development and function …
that maternal obesity has a negative influence on placental development and function …
Activation of placental insulin and mTOR signaling in a mouse model of maternal obesity associated with fetal overgrowth
FJ Rosario, TL Powell… - American Journal of …, 2016 - journals.physiology.org
Fetal overgrowth is common in obese women and is associated with perinatal complications
and increased risk for the child to develop metabolic syndrome later in life. Placental nutrient …
and increased risk for the child to develop metabolic syndrome later in life. Placental nutrient …
Maternal body weight and gestational diabetes differentially influence placental and pregnancy outcomes
J Martino, S Sebert, MT Segura… - The Journal of …, 2016 - academic.oup.com
Context: Maternal obesity and gestational diabetes mellitus (GDM) can both contribute to
adverse neonatal outcomes. The extent to which this may be mediated by differences in …
adverse neonatal outcomes. The extent to which this may be mediated by differences in …
Obesity and the placenta: a consideration of nutrient exchange mechanisms in relation to aberrant fetal growth
The obesity epidemic, including childhood obesity, is rapidly gaining strength as one of the
most significant challenges to the health of the global community in the 21st Century. The …
most significant challenges to the health of the global community in the 21st Century. The …
Maternal obesity: new placental paradigms unfolded
C Brombach, W Tong, DA Giussani - Trends in molecular medicine, 2022 - cell.com
The prevalence of maternal obesity is increasing at an alarming rate, and is providing a
major challenge for obstetric practice. Adverse effects on maternal and fetal health are …
major challenge for obstetric practice. Adverse effects on maternal and fetal health are …
Maternal obesity, metabolism, and pregnancy outcomes
JC King - Annu. Rev. Nutr., 2006 - annualreviews.org
▪ Abstract About one third of all pregnant women in the United States are obese. Maternal
obesity at conception alters gestational metabolic adjustments and affects placental …
obesity at conception alters gestational metabolic adjustments and affects placental …
Maternal prepregnancy obesity is associated with higher risk of placental pathological lesions
L Huang, J Liu, L Feng, Y Chen, J Zhang, W Wang - Placenta, 2014 - Elsevier
Introduction Prepregnancy obesity is associated with increased morbidity and mortality for
mother and offspring. The objective of our study is to estimate the effect of maternal …
mother and offspring. The objective of our study is to estimate the effect of maternal …
Feto-placental adaptations to maternal obesity in the baboon
D Farley, ME Tejero, AG Comuzzie, PB Higgins, L Cox… - Placenta, 2009 - Elsevier
Maternal obesity is present in 20–34% of pregnant women and has been associated with
both intrauterine growth restriction and large-for-gestational age fetuses. While fetal and …
both intrauterine growth restriction and large-for-gestational age fetuses. While fetal and …