Reactive oxygen species (ROS) are generated during mitochondrial oxidative metabolism
as well as in cellular response to xenobiotics, cytokines, and bacterial invasion. Oxidative …

Reactive oxygen species (ROS) including superoxide anion and hydrogen peroxide (H 2 O
2) are thought to be byproducts of aerobic respiration with damaging effects on DNA …

Reactive oxygen species (ROS) are generated as by-products of cellular metabolism,
primarily in the mitochondria. When cellular production of ROS overwhelms its antioxidant …

Reactive oxygen species (ROS) have been shown to be toxic but also function as signalling
molecules. This biological paradox underlies mechanisms that are important for the integrity …

Oxidative stress refers to elevated intracellular levels of reactive oxygen species (ROS) that
cause damage to lipids, proteins and DNA. Oxidative stress has been linked to a myriad of …

Although historically viewed as purely harmful, recent evidence suggests that reactive
oxygen species (ROS) function as important physiological regulators of intracellular …

Reactive oxygen species (ROS) are well known for their role in mediating both physiological
and pathophysiological signal transduction. Enzymes and subcellular compartments that …

Redox reactions are intrinsically linked to energy metabolism. Therefore, redox processes
are indispensable for organismal physiology and life itself. The term reactive oxygen species …

Oxidative stress is an increase in the reduction potential or a large decrease in the reducing
capacity of the cellular redox couples. A particularly destructive aspect of oxidative stress is …

Reactive oxygen species (ROS) were once considered to be deleterious agents,
contributing to a vast range of pathologies. But, now their protective effects are being …