Black-phosphorus-nanosheet-reinforced coating of implants for sequential biofilm ablation and bone fracture healing acceleration

B Yuan, X Zhou, Y Li, Y Zhao, M Xue… - … Applied Materials & …, 2022 - ACS Publications
Incurable implant-related infection may cause catastrophic consequences due to the
existence of a biofilm that resists the infiltration of host immune cells and antibiotics …

ZnL2-BPs Integrated Bone Scaffold under Sequential Photothermal Mediation: A Win–Win Strategy Delivering Antibacterial Therapy and Fostering Osteogenesis …

Y Wu, Q Liao, L Wu, Y Luo, W Zhang, M Guan, H Pan… - ACS …, 2021 - ACS Publications
Implant-related infections are serious complications after bone surgery and can compromise
the intended functions of artificial implants, leading to surgical failure and even amputation …

Designer dual therapy nanolayered implant coatings eradicate biofilms and accelerate bone tissue repair

J Min, KY Choi, EC Dreaden, RF Padera, RD Braatz… - ACS …, 2016 - ACS Publications
Infections associated with orthopedic implants cause increased morbidity and significant
healthcare cost. A prolonged and expensive two-stage procedure requiring two surgical …

Combined photothermal and sonodynamic therapy using a 2D black phosphorus nanosheets loaded coating for efficient bacterial inhibition and bone-implant …

J Zeng, C Gu, X Geng, K Lin, Y Xie, X Chen - Biomaterials, 2023 - Elsevier
Surgical site infection (SSI) remains a major threat for implant failure in orthopedics. Herein,
we report a dual-functional coating on Ti implants (named Ti/PDA/BP) with the integration of …

pH-Responsive nanoplatform synergistic gas/photothermal therapy to eliminate biofilms in poly (L-lactic acid) scaffolds

G Qian, Y Mao, H Zhao, L Zhang, L Xiong… - Journal of Materials …, 2024 - pubs.rsc.org
To date, implant-associated infection is still a significant clinical challenge, which cannot be
effectively eliminated by single therapies due to the formation of microbial biofilms. Herein, a …

2D‐black‐phosphorus‐reinforced 3D‐printed scaffolds: a stepwise countermeasure for osteosarcoma

B Yang, J Yin, Y Chen, S Pan, H Yao… - Advanced …, 2018 - Wiley Online Library
With the ever‐deeper understanding of nano–bio interactions and the development of
fabrication methodologies of nanomaterials, various therapeutic platforms based on …

Surface-mediated bone tissue morphogenesis from tunable nanolayered implant coatings

NJ Shah, MN Hyder, JS Moskowitz… - Science translational …, 2013 - science.org
The functional success of a biomedical implant critically depends on its stable bonding with
the host tissue. Aseptic implant loosening accounts for more than half of all joint replacement …

Boron-incorporated micro/nano-topographical calcium silicate coating dictates osteo/angio-genesis and inflammatory response toward enhanced osseointegration

K Li, X Lu, S Liu, X Wu, Y Xie, X Zheng - Biological Trace Element …, 2021 - Springer
Orthopedic implant coatings with optimal surface features to achieve favorable osteo/angio-
genesis and inflammatory response would be of great importance. However, to date, few …

Biocompatible hierarchical zwitterionic polymer brushes with bacterial phosphatase activated antibacterial activity

L Sun, L Song, X Zhang, S Yuan, S Luan - Journal of Materials Science & …, 2022 - Elsevier
Hierarchical polymer brushes have been considered as an effective and promising method
for preventing implant-associated infections via multiple antibacterial mechanisms. Herein, a …

Antibacterial and hydroxyapatite-forming coating for biomedical implants based on polypeptide-functionalized titania nanospikes

Q Gao, T Feng, D Huang, P Liu, P Lin, Y Wu, Z Ye… - Biomaterials …, 2020 - pubs.rsc.org
Titanium (Ti)-based implants often suffer from detrimental bacterial adhesion and inefficient
healing, so it is crucial to design a dual-functional coating that prevents bacterial infection …