Engineered biomaterials for in situ tissue regeneration

AK Gaharwar, I Singh, A Khademhosseini - Nature Reviews Materials, 2020 - nature.com
In situ tissue regeneration harnesses the body's regenerative potential to control cell
functions for tissue repair. The design of biomaterials for in situ tissue engineering requires …

[HTML][HTML] Biomaterials for recruiting and activating endogenous stem cells in situ tissue regeneration

I Safina, MC Embree - Acta biomaterialia, 2022 - Elsevier
Over the past two decades in situ tissue engineering has emerged as a new approach
where biomaterials are used to harness the body's own stem/progenitor cells to regenerate …

In situ tissue regeneration through host stem cell recruitment

IK Ko, SJ Lee, A Atala, JJ Yoo - Experimental & molecular medicine, 2013 - nature.com
The field of tissue engineering has made steady progress in translating various tissue
applications. Although the classical tissue engineering strategy, which involves the use of …

From In Vitro to In Situ Tissue Engineering

D Sengupta, SD Waldman, S Li - Annals of biomedical engineering, 2014 - Springer
In vitro tissue engineering enables the fabrication of functional tissues for tissue
replacement. In addition, it allows us to build useful physiological and pathological models …

Tissue repair and regeneration with endogenous stem cells

H Xia, X Li, W Gao, X Fu, RH Fang, L Zhang… - Nature Reviews …, 2018 - nature.com
In contrast to non-mammalian vertebrates, mammals and humans have limited innate
capacity for the self-regeneration of tissues and organs owing to differences in genetics …

Biomimetic materials for tissue engineering

PX Ma - Advanced drug delivery reviews, 2008 - Elsevier
Tissue engineering and regenerative medicine is an exciting research area that aims at
regenerative alternatives to harvested tissues for transplantation. Biomaterials play a pivotal …

Harnessing the innate and adaptive immune system for tissue repair and regeneration: Considering more than macrophages

LC Shanley, OR Mahon, DJ Kelly, A Dunne - Acta Biomaterialia, 2021 - Elsevier
Tissue healing and regeneration is a complex, choreographed, spatiotemporal process
involving a plethora of cell types, the activity of which is stringently regulated in order for …

Constructing a cell microenvironment with biomaterial scaffolds for stem cell therapy

X Zhao, Q Li, Z Guo, Z Li - Stem Cell Research & Therapy, 2021 - Springer
Stem cell therapy is widely recognized as a promising strategy for exerting therapeutic
effects after injury in degenerative diseases. However, limitations such as low cell retention …

Tissue engineering tools for modulation of the immune response

RM Boehler, JG Graham, LD Shea - Biotechniques, 2011 - Future Science
Tissue engineering scaffolds have emerged as a powerful tool within regenerative medicine.
These materials are being designed to create environments that promote regeneration …

New materials for tissue engineering: towards greater control over the biological response

G Chan, DJ Mooney - Trends in biotechnology, 2008 - cell.com
One goal of tissue engineering is to replace lost or compromised tissue function, and an
approach to this is to control the interplay between materials (scaffolds), cells and growth …