概要 非ステロイド性抗炎症薬 (NSAIDs) は骨折の治癒を阻害することが知られている. 我々は,
cyclooxygenase-2 選択的 NSAIDs であるセレコキシブが, 骨芽細胞においてその分化に重要な …

Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to impair bone healing.
We previously reported that in colon cancer cells, celecoxib, a COX-2-selective NSAID …

abstract Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to impair bone
healing. We previously reported that in colon cancer cells, celecoxib, a COX-2-selective …

Non‐steroidal anti‐inflammatory drugs (NSAID s) exert their effects primarily by inhibiting the
activity of cyclooxygenase (COX), thus suppressing prostaglandin synthesis. Some NSAID s …

Corticosteroid and COX-2 selective and non-selective nonsteroidal anti-inflammatory drugs
(NSAIDs) were reported to suppress bone repair and remodeling in vivo1. Glucocorticoid …

Previous reports indicated that specific cyclooxygenase-2 (COX-2) inhibitor suppresses
osteoarthritis (OA). This study aimed to further explore the possible mechanism of Rofecoxib …

Introduction: Nonsteroidal anti-inflammatory drugs (NSAIDs) have been reported to
suppress bone repair and remodeling in vivo. Our previous studies showed that NSAIDs …

Non-steroidal anti-inflammatory drugs (NSAIDs), including cyclooxygenase-2 (COX-2)-
selective NSAIDs, are associated with adverse effects on bone tissue. These drugs are …

The effects of a short course of a COX‐2 inhibitor on bone healing when the drug is
discontinued are unknown. We examined the effects of rofecoxib on bone ingrowth over a 6 …

Abstract Cyclooxygenase-2 (COX-2) 는 염증시 특징적으로 유발되는 단백질로 salicylate 로
억제됨은 주지의 사실이다. 하지만 arachidonic pathway 외 다른 신호전달 기전에 관한 연구는 …