[HTML][HTML] A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from …
C Andradi-Brown, JS Wichers-Misterek, H von Thien… - Elife, 2024 - elifesciences.org
The pathogenesis of severe Plasmodium falciparum malaria involves cytoadhesive
microvascular sequestration of infected erythrocytes, mediated by P. falciparum erythrocyte …
microvascular sequestration of infected erythrocytes, mediated by P. falciparum erythrocyte …
Successful Profiling of Plasmodium falciparum var Gene Expression in Clinical Samples via a Custom Capture Array
ABSTRACT var genes encode Plasmodium falciparum erythrocyte membrane protein-1
(PfEMP1) antigens. These highly diverse antigens are displayed on the surface of infected …
(PfEMP1) antigens. These highly diverse antigens are displayed on the surface of infected …
Analysis of single-cell gene transcription by RNA fluorescent in situ hybridization (FISH)
E Ronander, DC Bengtsson, L Joergensen… - JoVE (Journal of …, 2012 - jove.com
Adhesion of Plasmodium falciparum infected erythrocytes (IE) to human endothelial
receptors during malaria infections is mediated by expression of PfEMP1 protein variants …
receptors during malaria infections is mediated by expression of PfEMP1 protein variants …
[HTML][HTML] Homology blocks of Plasmodium falciparum var genes and clinically distinct forms of severe malaria in a local population
MM Rorick, TS Rask, EB Baskerville, KP Day… - BMC microbiology, 2013 - Springer
Background The primary target of the human immune response to the malaria parasite
Plasmodium falciparum, P. falciparum erythrocyte membrane protein 1 (PfEMP1), is …
Plasmodium falciparum, P. falciparum erythrocyte membrane protein 1 (PfEMP1), is …
[HTML][HTML] From In Vivo to In Vitro: Dynamic Analysis of Plasmodium falciparum var Gene Expression Patterns of Patient Isolates during Adaptation to Culture
Q Zhang, Y Zhang, Y Huang, X Xue, H Yan, X Sun… - PLoS …, 2011 - journals.plos.org
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), encoded by the var gene
family, plays a crucial role in disease virulence through its involvement in binding to various …
family, plays a crucial role in disease virulence through its involvement in binding to various …
[HTML][HTML] Common virulence gene expression in adult first-time infected malaria patients and severe cases
Sequestration of Plasmodium falciparum (P. falciparum)-infected erythrocytes to host
endothelium through the parasite-derived P. falciparum erythrocyte membrane protein 1 (Pf …
endothelium through the parasite-derived P. falciparum erythrocyte membrane protein 1 (Pf …
[HTML][HTML] Controlled human malaria infection with Plasmodium falciparum demonstrates impact of naturally acquired immunity on virulence gene expression
The pathogenesis of Plasmodium falciparum malaria is linked to the variant surface antigen
Pf EMP1, which mediates tethering of infected erythrocytes to the host endothelium and is …
Pf EMP1, which mediates tethering of infected erythrocytes to the host endothelium and is …
[HTML][HTML] Refining the transcriptome of the human malaria parasite Plasmodium falciparum using amplification-free RNA-seq
Background Plasmodium parasites undergo several major developmental transitions during
their complex lifecycle, which are enabled by precisely ordered gene expression programs …
their complex lifecycle, which are enabled by precisely ordered gene expression programs …
[HTML][HTML] NSR-seq transcriptional profiling enables identification of a gene signature of Plasmodium falciparum parasites infecting children
M Vignali, CD Armour, J Chen… - The Journal of …, 2011 - Am Soc Clin Investig
Malaria caused by Plasmodium falciparum results in approximately 1 million annual deaths
worldwide, with young children and pregnant mothers at highest risk. Disease severity might …
worldwide, with young children and pregnant mothers at highest risk. Disease severity might …
[HTML][HTML] New var reconstruction algorithm exposes high var sequence diversity in a single geographic location in Mali
A Dara, EF Drábek, MA Travassos, KA Moser… - Genome Medicine, 2017 - Springer
Background Encoded by the var gene family, highly variable Plasmodium falciparum
erythrocyte membrane protein-1 (PfEMP1) proteins mediate tissue-specific cytoadherence of …
erythrocyte membrane protein-1 (PfEMP1) proteins mediate tissue-specific cytoadherence of …