Parkinson's disease (PD) is a common neurodegenerative disease that primarily affects the
elderly, significantly impacting patients' health and quality of life. While most genetic studies …

Genetic variation contributes significantly to Parkinson's disease (PD) risk, onset, and
progression. However, most of the common genetic variation that contributes to PD is still …

The pathophysiology of Parkinson's disease (PD) is a complex process of the interaction
between genetic and environmental factors. Studies on the genetic component of PD have …

Background Most sequencing studies in Parkinson's disease (PD) have focused on either a
particular gene, primarily in familial and early onset PD samples, or on screening single …

Background: The pathophysiology of Parkinson's disease (PD) is a complex interaction
process between genetic and environmental factors. In this study, we approached this …

Parkinson's disease (PD) is a progressive neurodegenerative disorder resulting in
significant damage to dopaminergic neurons within the basal ganglia of the brain leading to …

Background Parkinson's disease (PD) is complex and heterogeneous. The numerous
susceptibility loci that have been identified reaffirm the complexity of PD but do not fully …

Over the past 20 years, numerous robust analyses have identified over 20 genes related to
familial Parkinson's disease (PD), thereby uncovering its molecular underpinnings and …

We performed a two-tiered, whole-genome association study of Parkinson disease (PD). For
tier 1, we individually genotyped 198,345 uniformly spaced and informative single …

Two decades after the identification of SNCA as the first causative gene in Parkinson's
disease (PD) and the subsequent understanding that genetic factors play a substantial role …