Contributions of the Microbiome-Derived Metabolome for Risk Assessment and Prognostication of Pancreatic Cancer
RA León-Letelier, R Dou, J Vykoukal… - Clinical …, 2024 - academic.oup.com
Background Increasing evidence implicates microbiome involvement in the development
and progression of pancreatic ductal adenocarcinoma (PDAC). Studies suggest that reflux of …
and progression of pancreatic ductal adenocarcinoma (PDAC). Studies suggest that reflux of …
Integrated analysis of microbiome and metabolome reveals signatures in PDAC tumorigenesis and prognosis
Y Fang, X Liu, J Ren, X Wang, F Zhou… - Microbiology …, 2024 - journals.asm.org
Pancreatic cancer, predominantly pancreatic ductal adenocarcinoma (PDAC), is one of the
most malignant tumors of the digestive system. Emerging evidence suggests the …
most malignant tumors of the digestive system. Emerging evidence suggests the …
[HTML][HTML] Decoding the microbiota metabolome in hepatobiliary and pancreatic cancers: Pathways to precision diagnostics and targeted therapeutics
Y Xu, J Le, J Qin, Y Zhang, J Yang, Z Chen, C Li… - Pharmacological …, 2024 - Elsevier
We delve into the critical role of the gut microbiota and its metabolites in the pathogenesis
and progression of hepatobiliary and pancreatic (HBP) cancers, illuminating an urgent need …
and progression of hepatobiliary and pancreatic (HBP) cancers, illuminating an urgent need …
The role of microbiome in pancreatic cancer
Recent studies of the human microbiome have offered new insights into how the microbiome
can impact cancer development and treatment. Specifically, in pancreatic ductal …
can impact cancer development and treatment. Specifically, in pancreatic ductal …
A blood-based metabolomic signature predictive of risk for pancreatic cancer
Emerging evidence implicates microbiome involvement in the development of pancreatic
cancer (PaCa). Here, we investigate whether increases in circulating microbial-related …
cancer (PaCa). Here, we investigate whether increases in circulating microbial-related …
Metabolic characterization of plasma and cyst fluid from cystic precursors to pancreatic cancer patients reveal metabolic signatures of bacterial infection
A Morgell, JA Reisz, Z Ateeb, H Davanian… - Journal of Proteome …, 2021 - ACS Publications
Pancreatic cancer is the seventh leading cause of cancer-related death worldwide, with a 5
year survival rate as low as 9%. One factor complicating the management of pancreatic …
year survival rate as low as 9%. One factor complicating the management of pancreatic …
Microbiome and pancreatic cancer: Time to think about chemotherapy
J de Castilhos, K Tillmanns, J Blessing, A Laraño… - Gut …, 2024 - Taylor & Francis
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer characterized by
late diagnosis, rapid progression, and a high mortality rate. Its complex biology …
late diagnosis, rapid progression, and a high mortality rate. Its complex biology …
A comprehensive review of the current and future role of the microbiome in pancreatic ductal adenocarcinoma
N Merali, T Chouari, K Kayani, CJ Rayner, JI Jimenez… - Cancers, 2022 - mdpi.com
Simple Summary This review summarizes the current literature related to the microbiome
and pancreatic ductal adenocarcinoma (PDAC). The aim of this review is to explore the …
and pancreatic ductal adenocarcinoma (PDAC). The aim of this review is to explore the …
[HTML][HTML] Implications of the microbiome in the development and treatment of pancreatic cancer: Thinking outside of the box by looking inside the gut
Q Yu, C Jobin, RM Thomas - Neoplasia, 2021 - Elsevier
Pancreatic ductal adenocarcinoma is the third leading cause of cancer-related death in the
United States. As one of the most lethal cancer types, the prognosis for patients diagnosed …
United States. As one of the most lethal cancer types, the prognosis for patients diagnosed …
Oncobiosis and microbial metabolite signaling in pancreatic adenocarcinoma
Pancreatic adenocarcinoma is one of the most lethal cancers in both men and women, with
a median five-year survival of around 5%. Therefore, pancreatic adenocarcinoma represents …
a median five-year survival of around 5%. Therefore, pancreatic adenocarcinoma represents …
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