Background Sevoflurane exposure at brain developmental stages has been reported to
induce neurotoxicity and, subsequently, results in learning deficits at the juvenile age. In this …

Sevoflurane is one of the most commonly used volatile anaesthetics for children, but the
safety of prolonged or repeated clinical use of sevoflurane in infants or children is …

Background: Sevoflurane is a volatile anesthetic that is widely used in pediatric anesthesia
due to its low toxicity. However, whether neonatal exposure to sevoflurane induces long …

Early exposure to sevoflurane, an inhalation anesthetic, induces neurodegeneration in the
developing brain and subsequent long-term neurobehavioral abnormalities. Here, we …

The increasing usage of general anesthetics on young children and infants has drawn
extensive attention to the effects of these drugs on cognitive function later in life. Recent …

Currently sevoflurane is the volatile anesthetic most wildly used in pediatric surgery.
Whether neonatal exposure to sevoflurane brings about a long-lasting adverse impact even …

Purpose Developmental exposure to volatile anesthetics has been associated with cognitive
deficits at adulthood. Rodent studies have revealed impairments in performance in learning …

Sevoflurane, one of the most commonly used anesthetic agents, has been demonstrated to
induce widespread neurodegeneration in the developing brain. We aimed to evaluate the …

Background Sevoflurane is an inhaled anesthetic commonly used in the pediatric. Recent
animal studies suggest that early exposure to high concentration of sevoflurane for a long …

Objective To examine whether neonatal exposure to sevoflurane induces autism‐like
behaviors in mice. Background There are continuing reports regarding the potential …