An update on the ability of St. John's wort to affect the metabolism of other drugs

R Rahimi, M Abdollahi - Expert opinion on drug metabolism & …, 2012 - Taylor & Francis
Introduction: Hypericum perforatum (HP), more commonly known as St. John's wort, is a
popular medicinal herb used for the treatment of depression. HP affects the …

Clinical risks of St John's Wort (Hypericum perforatum) co-administration

S Soleymani, R Bahramsoltani, R Rahimi… - Expert opinion on …, 2017 - Taylor & Francis
ABSTRACT Introduction: St. John's wort (SJW) is a common medicinal herb used for the
treatment of mild to moderate depression. Hyperforin, one of the chief components of SJW …

Pharmacokinetic interactions of drugs with St John's wort

S Zhou, E Chan, SQ Pan, M Huang… - Journal of …, 2004 - journals.sagepub.com
There is a worldwide increasing use of herbs which are often administered in combination
with therapeutic drugs, raising the potential for herb-drug interactions. St John's wort …

Drug interactions with St John's wort: mechanisms and clinical implications

M Mannel - Drug safety, 2004 - Springer
The purpose of this paper is to review preclinical and clinical evidence relating to drug
interactions with preparations of the medicinal herb St John's wort (Hypericum perforatum) …

An update on clinical drug interactions with the herbal antidepressant St. John's wort

SF Zhou, X Lai - Current drug metabolism, 2008 - ingentaconnect.com
St. John's wort (Hypericum perforatum, SJW) is one of the most commonly used herbal
antidepressants for the treatment of minor to moderate depression. Limited clinical trials …

The effects of St John's wort (Hypericum perforatum) on human cytochrome P450 activity

Z Wang, JC Gorski, MA Hamman… - Clinical …, 2001 - Wiley Online Library
Background St John's wort (Hypericum perforatum) is a popular over‐the‐counter dietary
supplement and herbal remedy that has been implicated in drug interactions with substrates …

Herb–Drug Interactions with St John's Wort (Hypericum perforatum): an Update on Clinical Observations

F Borrelli, AA Izzo - The AAPS journal, 2009 - Springer
St John's wort (SJW) extracts, prepared from the aerial parts of Hypericum perforatum,
contain numerous pharmacologically active ingredients, including naphthodianthrones (eg …

The growing knowledge of St. John's wort (Hypericum perforatum L) drug interactions and their clinical significance

PM Biffignandi, AR Bilia - Current therapeutic research, 2000 - Elsevier
OBJECTIVE: This review discusses drug interactions with St. John's wort (Hypericum
perforatum L), and their clinical relevance. BACKGROUND: Herbal medicines are being …

Interactions between herbal medicines and prescribed drugs: an updated systematic review

AA Izzo, E Ernst - Drugs, 2009 - Springer
The concomitant use of herbal medicines and pharmacotherapy is wide spread. We have
reviewed the literature to determine the possible interactions between seven popular herbal …

Drug interactions with St. John's Wort (Hypericum perforatum): a review of the clinical evidence.

AA Izzo - International journal of clinical pharmacology and …, 2004 - europepmc.org
St. John's Wort (SJW, Hypericum perforatum) is effective in mild-to-moderate depression. As
a monotherapy, SJW has an encouraging safety profile. However, numerous reports indicate …