[HTML][HTML] Phosphorylcholine monoclonal antibody therapy decreases intraplaque angiogenesis and intraplaque hemorrhage in murine vein grafts
F Baganha, TJ Sluiter, RCM de Jong… - International Journal of …, 2022 - mdpi.com
Phosphorylcholine (PC) is one of the main oxLDL epitopes playing a central role in
atherosclerosis, due to its atherogenic and proinflammatory effects. PC can be cleared by …
atherosclerosis, due to its atherogenic and proinflammatory effects. PC can be cleared by …
Passive immunization with monoclonal IgM antibodies against phosphorylcholine reduces accelerated vein graft atherosclerosis in apolipoprotein E-null mice
JR Faria-Neto, KY Chyu, X Li, PC Dimayuga, C Ferreira… - Atherosclerosis, 2006 - Elsevier
Phosphorylcholine (PC) headgroup is one of the neoantigens exposed by LDL oxidation
that can elicit an immune response. Active immunization with Streptococcus pneumoniae …
that can elicit an immune response. Active immunization with Streptococcus pneumoniae …
[HTML][HTML] Low levels of a natural IgM antibody are associated with vein graft stenosis and failure
M Sobel, KI Moreno, M Yagi, TR Kohler, GL Tang… - Journal of vascular …, 2013 - Elsevier
Background All humans have natural, protective antibodies directed against
phosphorylcholine (PC) epitopes, a common inflammatory danger signal appearing at sites …
phosphorylcholine (PC) epitopes, a common inflammatory danger signal appearing at sites …
Antibodies against phosphorylcholine and protection against atherosclerosis, cardiovascular disease and chronic inflammation
J Frostegård - Expert Review of Clinical Immunology, 2022 - Taylor & Francis
Introduction Chronic inflammatory diseases include cardiovascular disease (CVD),
atherosclerosis, rheumatic and autoimmune diseases, and others, constituting a large part of …
atherosclerosis, rheumatic and autoimmune diseases, and others, constituting a large part of …
Phosphorylcholine-targeting immunization reduces atherosclerosis
G Caligiuri, J Khallou-Laschet, M Vandaele… - Journal of the American …, 2007 - jacc.org
Objectives: The present study evaluated the effect of phosphorylcholine (PC) immunization
on the extent of experimental atherosclerosis. Background: Immunization against oxidized …
on the extent of experimental atherosclerosis. Background: Immunization against oxidized …
Identification of IgG1 isotype phosphorylcholine antibodies for the treatment of inflammatory cardiovascular diseases
MR de Vries, MM Ewing, RCM de Jong… - Journal of Internal …, 2021 - Wiley Online Library
Background Phosphorylcholine (PC) is an important pro‐inflammatory damage‐associated
molecular pattern. Previous data have shown that natural IgM anti‐PC protects against …
molecular pattern. Previous data have shown that natural IgM anti‐PC protects against …
[HTML][HTML] Anti-phosphorylcholine IgM, an anti-inflammatory mediator, predicts peripheral vein graft failure: a prospective observational study
M Sobel, M Yagi, K Moreno, TR Kohler, GL Tang… - European Journal of …, 2019 - Elsevier
Objectives One third of infrainguinal vein bypasses may fail within the first 1.5 years. Pro-and
anti-inflammatory mechanisms are thought to be involved in these graft stenoses and …
anti-inflammatory mechanisms are thought to be involved in these graft stenoses and …
[图书][B] Natural antibodies against phosphorylcholine as potential protective factors in atherosclerosis, cardiovascular disease and systemic lupus erythematosus
J Su - 2009 - search.proquest.com
Natural antibodies against phosphorylcholine as potential protective factors in atherosclerosis,
cardiovascular disease and sy Page 1 Institutionen för Medicin, Enheten för Akutmedicin …
cardiovascular disease and sy Page 1 Institutionen för Medicin, Enheten för Akutmedicin …
Low levels of natural IgM antibodies against phosphorylcholine are independently associated with vascular remodeling in patients with coronary artery disease
CA Gleissner, C Erbel, J Haeussler… - Clinical Research in …, 2015 - Springer
Low anti-phosphorylcholine (PC) IgM plasma levels have been associated with increased
incidence of adverse events in coronary artery disease (CAD). The underlying mechanisms …
incidence of adverse events in coronary artery disease (CAD). The underlying mechanisms …
Low level natural antibodies against phosphorylcholine: a novel risk marker and potential mechanism in atherosclerosis and cardiovascular disease
J Frostegård - Clinical immunology, 2010 - Elsevier
Atherosclerosis is an inflammatory condition characterised by an abundance of activated
immunocompetent cells in plaques which cause cardiovascular disease (CVD) when they …
immunocompetent cells in plaques which cause cardiovascular disease (CVD) when they …