Linc00941 fuels ribogenesis and protein synthesis by supporting robust cMYC translation in malignant pleural mesothelioma

M Gugnoni, E Lorenzini, F Torricelli, B Donati… - Cancer Letters, 2024 - Elsevier
Malignant pleural mesothelioma is a rare and lethal cancer caused by exposure to asbestos.
The highly inflammatory environment caused by fibers accumulation forces cells to undergo …

miR-206 inhibits pleural mesothelioma by targeting an active KRAS/CDK4/CCND1 pathway

A Singh, R Pahwa, L Zhang, N Pruett, RT Ripley… - Cancer Research, 2018 - AACR
Introduction: Since there remains no effective, durable chemotherapy against malignant
pleural mesothelioma (MPM), we propose to leverage microRNA (miR)-based approaches …

Overexpression of LINC00152 correlates with poor patient survival and knockdown impairs cell proliferation in lung cancer

S Feng, J Zhang, W Su, S Bai, L Xiao, X Chen, J Lin… - Scientific reports, 2017 - nature.com
We employed RNA sequencing analysis to reveal dysregulated lncRNAs in lung cancer
utilizing 461 lung adenocarcinomas and 156 normal lung tissues from 3 separate cohorts …

Long non coding RNAs (lncRNAs) are dysregulated in malignant pleural mesothelioma (MPM)

CM Wright, MB Kirschner, YY Cheng, KJ O'Byrne… - PLoS …, 2013 - journals.plos.org
Malignant Pleural Mesothelioma (MPM) is an aggressive cancer that is often diagnosed at
an advanced stage and is characterized by a long latency period (20–40 years between …

A noncoding RNA LINC00504 interacts with c‐Myc to regulate tumor metabolism in colon cancer

J Feng, J Ma, S Liu, J Wang… - Journal of cellular …, 2019 - Wiley Online Library
Accumulating evidence has shown a critical role of long‐non‐coding RNAs (lncRNAs)
during multiple tumor progression. However, the potential functions of LINC00504 in colon …

LncRNAs and related molecular basis in malignant pleural mesothelioma: Challenges and potential

X Xu, H Li, M Xie, Z Zhou, D Wang, W Mao - Critical Reviews in Oncology …, 2023 - Elsevier
Malignant pleural mesothelioma (MPM) is a rare but invasive cancer, which mainly arises
from mesothelial tissues of pleura, peritoneum and pericardium. Despite significant …

Role of LINC00152 in non-small cell lung cancer

H Yu, S Li - Journal of Zhejiang University-SCIENCE B, 2020 - Springer
Non-small cell lung cancer (NSCLC) accounts for about 85% of all lung cancer cases. The
pathogenesis of NSCLC involves complex gene networks that include different types of non …

An RNAi-based screen reveals PLK1, CDK1 and NDC80 as potential therapeutic targets in malignant pleural mesothelioma

A Linton, YY Cheng, K Griggs, MB Kirschner… - British journal of …, 2014 - nature.com
Background: Malignant pleural mesothelioma (MPM) is an aggressive tumour originating in
the thoracic mesothelium. Prognosis remains poor with 9-to 12-month median survival, and …

[HTML][HTML] MicroRNA-206 suppresses mesothelioma progression via the Ras signaling axis

A Singh, N Pruett, R Pahwa, AP Mahajan… - … Therapy-Nucleic Acids, 2021 - cell.com
Malignant pleural mesothelioma (MPM) is an incurable surface neoplasm with peculiar
pathobiology. MPM proliferates by using the tyrosine-kinase-Ras pathway. Despite …

[HTML][HTML] Long non-coding RNA LINC01116 is overexpressed in lung adenocarcinoma and promotes tumor proliferation and metastasis

L Zeng, X Lyu, J Yuan, W Wang, N Zhao… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Long non-coding RNA LINC01116 is involved in the occurrence and progression of a variety
of cancers. However, the specific role of LINC01116 in lung adenocarcinoma (LUAD) …