Neurodegenerative disorders affect almost 30 million individuals leading to disability and
death. These disorders are characterized by pathological changes in disease-specific areas …

When subjected to excessive oxidative stress, neurons may respond adaptively to overcome
the stress, or they may activate a programmed cell death pathway called apoptosis …

Degeneration and death of neurons is the fundamental process responsible for the clinical
manifestations of many different neurological disorders of aging, incuding Alzheimer's …

Progressive cell loss in specific neuronal populations often associated with typical
cytoskeletal protein aggregations is a pathological hallmark of neurodegenerative disorders …

In recent years, the investigation of erroneous regulation of apoptotic mechanisms during
acute and chronic injury of neuronal cells has gained increasing attention. Besides acute …

Objective: Progressive cell loss in specific neuronal populations is the prominent
pathological hallmark of neurodegenerative diseases, but its molecular basis remains …

Neuronal death underlies the symptoms of many human neurological disorders, including
Alzheimer's, Parkinson's and Huntington's diseases, stroke, and amyotrophic lateral …

Apoptosis has been well documented to play a significant role in cell loss during
neurodengerative disorders, such as stroke, Parkinson disease, and Alzheimer's disease. In …

Apoptosis mediates the precise and programmed natural death of neurons and is a
physiologically important process in neurogenesis during maturation of the central nervous …

Alzheimer's disease (AD) and Parkinson's disease (PD) are two of the most significant
neurodegenerative disorders in the developed world. However, although these diseases …