Kidney disease is one of the most serious manifestations of systemic lupus erythematosus
(SLE). Despite the improvement in the medical care of SLE in the past two decades, the …

Current treatment of severe lupus nephritis is unsatisfactory in terms of both outcome and
toxicity. To improve the efficacy and decrease the adverse effects of immunosuppression, it …

Lupus nephritis (LN) has significant impact on the outcome of patients with systemic lupus
erythematosus (SLE). In the absence of any new breakthrough for management of LN over …

Lupus nephritis (LN), a potentially destructive outcome of SLE, is a real challenge in the
management of SLE because of the difficulty in diagnosing its subclinical onset and …

Lupus nephritis (LN) represents the most severe organ manifestation of systemic lupus
erythematosus (SLE) in terms of morbidity and mortality. To reduce these risks, tremendous …

Biomarker development in lupus nephritis (LN) has traditionally relied on comparing the
characteristics of candidate markers to clinical findings in patients and controls from cross …

Renal involvement in patients with systemic lupus erythematosus in the form of severe lupus
nephritis is associated with a significant burden of morbidity and mortality. Conventional …

Lupus nephritis (LN) occurs in up to 60% of SLE patients, and is a leading cause of disability
and death. Current treatment of LN consists of a combination of high dose corticosteroids …

Systemic lupus erythematosus (SLE) is the prototypical autoimmune disease that can affect
any organ of the body. Multiple mechanisms may contribute to the pathophysiology of …

Systemic lupus erythematosus (SLE) is a chronic multifactorial autoimmune disease that
affects many organs, including the kidney. Lupus nephritis (LN) is a common manifestation …