Multiple reports for brain functional and structural alterations in patients with Crohn's disease
(CD) were published. The current study aimed to meta-analyze the existing neuroimaging …

Background Crohn's disease (CD) is a non-specific chronic inflammatory disease of the
gastrointestinal tract and is a phenotype of inflammatory bowel disease (IBD). The current …

Background Crohn's disease (CD) is a chronic intestinal disorder characterized by
overproduction of inflammatory cytokines and recurrent abdominal pain. Recently, brain …

Background The previous studies have demonstrated that patients with Crohn's disease in
remission (CD-R) have abnormal alterations in brain function. However, whether brain …

Background Crohn's disease (CD) is an inflammatory, chronic disorder that alternates
between a quiescent phase and inflammatory flare-ups. Research has begun to elucidate …

Abstract Introduction Evidence suggests that Crohn's disease (CD) pathophysiology goes
beyond the gastrointestinal tract and is also strongly associated with the brain. In particular …

Increasing evidence indicates that abnormal pain processing is present in the central
nervous system of patients with Crohn's disease (CD). The purposes of this study were to …

Crohn's disease is an acknowledged “brain–gut” disorder with unclear physiopathology.
This study aims to identify potential neuroimaging biomarkers of Crohn's disease. Gray …

Background: Crohn's disease (CD) is a subtype of inflammatory bowel disease caused by
immune-mediated inflammation in the gastrointestinal tract. The extent of morphologic brain …

Rationale and objectives To investigate alterations in the brain structure in patients with
Crohn's disease in activity (CD-A) and in remission (CD-R) compared to healthy controls …