Spinal cord injury (SCI) results in devastating patient outcomes with few treatment options. A
promising approach to improve outcomes following SCI involves the activation of …

Spinal cord injury (SCI) is a devastating condition with few treatment options. Metformin, a
classical antidiabetic and antioxidant, has extended its application to experimental SCI …

Metformin, a first-line drug for type-2 diabetes, has been shown to improve locomotor
recovery after spinal cord injury. However, there are studies reporting no beneficial effect …

Spinal cord injury (SCI) is a devastating disease that may lead to lifelong disability. Thus,
seeking for valid drugs that are beneficial to promoting axonal regrowth and elongation after …

Spinal cord injury (SCI) is one kind of severe trauma for central nervous system. Myelin
debris clearance and axon regeneration are essential for nerve regeneration after SCI …

Multiple Sclerosis (MS) is a chronic disease characterized by immune-mediated destruction
of myelinating oligodendroglia in the central nervous system. Loss of myelin leads to …

Multiple sclerosis (MS) is an autoimmune disease characterized by inflammation, death or
damage of oligodendrocytes, and axonal degeneration. Current MS treatments are non …

Resident neural stem and progenitor cells, collectively termed neural precursor cells
(NPCs), reside in a well-defined neurogenic niche in the subventricular zone (SVZ) and …

Background Multiple sclerosis (MS) is a devastating autoimmune disorder characterized by
oligodendrocytes (OLGs) loss and demyelination. In this study, we have examined the …

Individuals with demyelinating diseases often experience difficulties during social
interactions that are not well studied in preclinical models. Here, we describe a novel …