[HTML][HTML] Evaluation of synthon influence on ethenzamide–polyphenol pharmaceutical cocrystals

FJ Acebedo-Martínez, A Domínguez-Martín… - …, 2023 - pubs.rsc.org
The pharmaceutical cocrystal landscape of ethenzamide has been addressed during the
past years with the aim of improving its physicochemical properties, mainly solubility and …

Crystal structure landscape of ethenzamide: a physicochemical property study

KK Sarmah, K Boro, M Arhangelskis, R Thakuria - CrystEngComm, 2017 - pubs.rsc.org
Pharmaceutical cocrystals/cocrystal hydrate of ethenzamide (ETZ) with various hydroxy-acid
coformers namely 2, 4-dihydroxybenzoic acid (24DHBA), 3, 5-dihydroxybenzoic acid …

Pharmaceutical cocrystals of ethenzamide: structural, solubility and dissolution studies

S Aitipamula, ABH Wong, PS Chow, RBH Tan - CrystEngComm, 2012 - pubs.rsc.org
Pharmaceutical cocrystals involving an analgesic drug, ethenzamide (EA) and coformers,
such as salicylic acid (SA), 2-chloro-4-nitrobenzoic acid (CNBA), vanillic acid (VA), 4 …

Structural characterization and pharmaceutical properties of three novel cocrystals of ethenzamide with aliphatic dicarboxylic acids

A Kozak, PH Marek, E Pindelska - Journal of pharmaceutical sciences, 2019 - Elsevier
Ethenzamide (ET) was screened in cocrystallization experiments with pharmaceutically
acceptable coformer molecules to discover materials of improved physicochemical …

[HTML][HTML] Pharmaceutical cocrystals of ethenzamide: molecular structure analysis based on vibrational spectra and DFT calculations

M Wan, J Fang, J Xue, J Liu, J Qin, Z Hong… - International Journal of …, 2022 - mdpi.com
Pharmaceutical cocrystals can offer another advanced strategy for drug preparation and
development and can facilitate improvements to the physicochemical properties of active …

Cocrystals of ethenzamide: study of structural and physicochemical properties

VM Hariprasad, SK Nechipadappu… - Crystal Growth & …, 2016 - ACS Publications
Pharmaceutical cocrystals of an analgesic drug ethenzamide (ETZ) with various coformers,
namely, gallic acid (GA), 2-nitrobenzoic acid (2NB), 3-nitrobenzoic acid (3NB), 2, 4 …

Pharmaceutical properties of two ethenzamide-gentisic acid cocrystal polymorphs: Drug release profiles, spectroscopic studies and theoretical calculations

A Sokal, E Pindelska, L Szeleszczuk… - International journal of …, 2017 - Elsevier
The aim of this study was to evaluate the stability and solubility of the polymorphic forms of
the ethenzamide (ET)–gentisic acid (GA) cocrystals during standard technological …

Polymorphism and distinct physicochemical properties of the phloretin–nicotinamide cocrystal

S Aitipamula, LP Shan, KM Gupta - CrystEngComm, 2022 - pubs.rsc.org
The emergence of cocrystals as alternative solid forms for development of novel drug
products signifies the relevance of polymorphism studies in cocrystals. We report two novel …

Spectroscopic analysis of the influence of various external factors on ethenzamide-glutaric acid (1: 1) cocrystal formation

A Kozak, E Pindelska - European Journal of Pharmaceutical Sciences, 2019 - Elsevier
Cocrystal formation may affect manufacturability (flow, compaction and processability) as
well as solubility/dissolution, hygroscopicity and stability properties of drugs. Therefore …

[HTML][HTML] Rational Coformer Selection in the Development of 6-Propyl-2-thiouracil Pharmaceutical Cocrystals

FJ Acebedo-Martínez, C Alarcón-Payer… - Pharmaceuticals, 2023 - mdpi.com
Pharmaceutical multicomponent solids have proved to efficiently modulate the
physicochemical properties of active pharmaceutical ingredients. In this context …