Modern humans inhabit a variety of environments and are exposed to a plethora of selective
pressures, leading to multiple genetic adaptations to local environmental conditions. These …

The recent availability of genomic data has spurred many genome-wide studies of human
adaptation in different populations worldwide. Such studies have provided insights into …

The spread of modern humans across the globe has led to genetic adaptations to diverse
local environments. Recent developments in genomic technologies, statistical analyses, and …

The molecular basis of adaptation—and, in particular, the relative roles of protein-coding
versus gene expression changes—has long been the subject of speculation and debate …

Humans show tremendous phenotypic diversity across geographically distributed
populations, and much of this diversity undoubtedly results from genetic adaptations to …

After leaving sub-Saharan Africa around 50 000–100 000 years ago, anatomically modern
humans have quickly occupied extremely diverse environments. Human populations were …

Empowered by technology and sampling efforts designed to facilitate genome-wide
association mapping, human geneticists are now studying the geography of genetic …

Recent advances in genotyping technologies have facilitated genome-wide scans for
natural selection. Detecting targets of natural selection sheds light on human evolution and it …

Human populations use a variety of subsistence strategies to exploit an exceptionally broad
range of ecoregions and dietary components. These aspects of human environments have …

Humans inhabit a remarkably diverse range of environments, and adaptation through
natural selection has likely played a central role in the capacity to survive and thrive in …