Multi-parameter flow cytometry, molecular genetics, and cytogenetic studies have all
contributed to new classification of leukemia. In this review we discuss immunophenotypic …

Bone marrow cells of 325 adults with acute leukemia were immunophenotyped using a
panel of monoclonal antibodies proposed by the European Group for the Immunological …

This study prospectively analysed the relationships between immunophenotypic and
cytogenetic features of blast cells in 432 acute non-lymphoblastic leukemias (ANLL) at …

Abstract The t (12; 21)(p13; q22) fusion gene is the most frequent genetic lesion described in
precursor B cell acute lymphoblastic leukemia (ALL) of childhood occurring in a quarter of …

Using literature data on cytogenetic abnormalities in 3,612 cases of acute myeloid leukemia
(AML) and 1,551 cases of acute lymphocytic leukemia (ALL), we have attempted to quantify …

Conventional cytogenetic analysis currently stratifies acute myelogenous leukaemia (AML)
into prognostically relevant groups. However, approximately 50% of adult AMLs have …

Acquired chromosome aberrations are present in the marrow of most patients with acute
myeloid leukaemia (AML) at diagnosis. Cytogenetically, AML is a very heterogeneous …

Accurate subclassification of leukemia and the identification of prognostic determinants are
essential to guide therapy and to improve patients' outcome. According to present standards …

Modern classification systems for acute and chronic leukaemias are based on
cytomorphology, cytochemistry, immunophenotyping, immunogenetics and molecular …

Cytogenetic analyses in acute myeloid leukemia (AML) and acute lymphoblastic leukemia
(ALL) have revealed a great number of non-random chromosome abnormalities. In many …