Linking pathogenic mechanisms of alcoholic liver disease with clinical phenotypes

LE Nagy, WX Ding, G Cresci, P Saikia, VH Shah - Gastroenterology, 2016 - Elsevier
Alcoholic liver disease (ALD) develops in approximately 20% of alcoholic patients, with a
higher prevalence in females. ALD progression is marked by fatty liver and hepatocyte …

Recent advances in understanding of pathogenesis of alcohol-associated liver disease

X Wu, X Fan, T Miyata, A Kim… - Annual Review of …, 2023 - annualreviews.org
Alcohol-associated liver disease (ALD) is one of the major diseases arising from chronic
alcohol consumption and is one of the most common causes of liver-related morbidity and …

Alcoholic liver disease: mechanisms of injury and targeted treatment

A Louvet, P Mathurin - Nature reviews Gastroenterology & hepatology, 2015 - nature.com
Alcoholic liver disease (ALD) is a complex process that includes a wide spectrum of hepatic
lesions, from steatosis to cirrhosis. Cell injury, inflammation, oxidative stress, regeneration …

[HTML][HTML] Alcoholic liver disease: Current insights into cellular mechanisms

L Petagine, MG Zariwala, VB Patel - World Journal of Biological …, 2021 - ncbi.nlm.nih.gov
Alcoholic liver disease (ALD) due to chronic alcohol consumption is a significant global
disease burden and a leading cause of mortality. Alcohol abuse induces a myriad of …

Pathogenesis of alcoholic liver disease: interactions between parenchymal and non‐parenchymal cells

JI Cohen, LE Nagy - Journal of digestive diseases, 2011 - Wiley Online Library
The development of alcoholic liver disease (ALD) is a complex process involving both the
parenchymal and non‐parenchymal cells in the liver. The impact of ethanol on hepatocytes …

Alcoholic liver disease: pathogenesis and new therapeutic targets

B Gao, R Bataller - Gastroenterology, 2011 - Elsevier
Alcoholic liver disease (ALD) is a major cause of chronic liver disease worldwide and can
lead to fibrosis and cirrhosis. The latest surveillance report published by the National …

Pathogenesis of alcoholic liver disease: an update

T Kourkoumpetis, G Sood - Clinics in Liver Disease, 2019 - liver.theclinics.com
Alcohol abuse is the seventh leading risk factor for death and disability-adjusted lifeyears
globally and the first cause of death among people between 15 to 49 years of age. 1 …

Alcoholic liver disease: current mechanistic aspects with focus on their clinical relevance

R Teschke - Biomedicines, 2019 - mdpi.com
The spectrum of alcoholic liver disease (ALD) is broad and includes alcoholic fatty liver,
alcoholic steatohepatitis, alcoholic hepatitis, alcoholic fibrosis, alcoholic cirrhosis, and …

[HTML][HTML] Alcoholic liver disease: A current molecular and clinical perspective

K Ohashi, M Pimienta, E Seki - Liver research, 2018 - Elsevier
Heavy alcohol use is the cause of alcoholic liver disease (ALD). The ALD spectrum ranges
from alcoholic steatosis to steatohepatitis, fibrosis, and cirrhosis. In Western countries …

Alcoholic liver disease

HK Seitz, R Bataller, H Cortez-Pinto, B Gao… - Nature reviews Disease …, 2018 - nature.com
Alcoholic liver disease (ALD) is the most prevalent type of chronic liver disease worldwide.
ALD can progress from alcoholic fatty liver (AFL) to alcoholic steatohepatitis (ASH), which is …