Targeting the endocannabinoid system for the treatment of abdominal pain in irritable bowel syndrome

SM Brierley, B Greenwood-Van Meerveld… - Nature Reviews …, 2023 - nature.com
The management of visceral pain in patients with disorders of gut–brain interaction, notably
irritable bowel syndrome, presents a considerable clinical challenge, with few available …

The role of the endocannabinoid system in the pathophysiology and treatment of irritable bowel syndrome

MA Storr, B Yüce, CN Andrews… - Neurogastroenterology …, 2008 - Wiley Online Library
Irritable bowel syndrome (IBS) is a spectrum of disorders characterized by abdominal
discomfort and pain, associated with altered bowel habits. Though gut motility, secretion and …

Cannabinoids as gastrointestinal anti‐inflammatory drugs

A Fabisiak, J Fichna - Neurogastroenterology & Motility, 2017 - Wiley Online Library
In this mini‐review, we focus on the potential of the endocannabinoid system as a target for
novel therapies to treat gastrointestinal (GI) inflammation. We discuss the organization of the …

[HTML][HTML] Irritable bowel syndrome: manipulating the endocannabinoid system as first-line treatment

V Brugnatelli, F Turco, U Freo, G Zanette - Frontiers in neuroscience, 2020 - frontiersin.org
Irritable Bowel Syndrome (IBS) is a functional disorder characterized by abdominal pain,
spasms, and altered bowel movements, either predominantly diarrhea (IBS-D), or …

[HTML][HTML] Cannabinoids and opioids in the treatment of inflammatory bowel diseases

M Kienzl, M Storr, R Schicho - Clinical and translational …, 2020 - journals.lww.com
In traditional medicine, Cannabis sativa has been prescribed for a variety of diseases.
Today, the plant is largely known for its recreational purpose, but it may find a way back to …

Gut feelings about the endocannabinoid system

V Di Marzo, F Piscitelli - Neurogastroenterology & Motility, 2011 - Wiley Online Library
Stemming from the centuries‐old and well known effects of Cannabis on intestinal motility
and secretion, research on the role of the endocannabinoid system in gut function and …

[HTML][HTML] Cannabis and cannabis derivatives for abdominal pain management in inflammatory bowel disease

K Bogale, W Raup-Konsavage, S Dalessio… - Medical Cannabis and …, 2021 - karger.com
For centuries, cannabis and its components have been used to manage a wide variety of
symptoms associated with many illnesses. Gastrointestinal (GI) diseases are no exception in …

The role of the endocannabinoid system in the brain–gut axis

KA Sharkey, JW Wiley - Gastroenterology, 2016 - Elsevier
The actions of cannabis are mediated by receptors that are part of an endogenous
cannabinoid system. The endocannabinoid system (ECS) consists of the naturally occurring …

Cannabinoids and gastrointestinal motility: pharmacology, clinical effects, and potential therapeutics in humans

M Camilleri - Neurogastroenterology & Motility, 2018 - Wiley Online Library
Background Cannabinoid agents and cannabis are frequently used for relief of diverse
gastrointestinal symptoms. Purpose The objective of this article is to increase the awareness …

Endocannabinoids in the Gut

NV DiPatrizio - Cannabis and cannabinoid research, 2016 - liebertpub.com
Cannabis has been used medicinally for centuries to treat a variety of disorders, including
those associated with the gastrointestinal tract. The discovery of our bodies' own “cannabis …