Signaling pathways in inflammation and anti-inflammatory therapies

YT Yeung, F Aziz, A Guerrero-Castilla… - Current …, 2018 - ingentaconnect.com
During the past decade, an abundance of new evidence highlighted the importance of
inflammation in the development of chronic pathologies such as neurodegeneration, cancer …

MAPK signalling pathways as molecular targets for anti-inflammatory therapy—from molecular mechanisms to therapeutic benefits

B Kaminska - Biochimica et Biophysica Acta (BBA)-Proteins and …, 2005 - Elsevier
Excessive inflammation is becoming accepted as a critical factor in many human diseases,
including inflammatory and autoimmune disorders, neurodegenerative conditions, infection …

Recent advances in molecular pathways and therapeutic implications targeting neuroinflammation for Alzheimer's disease

R Dhapola, SS Hota, P Sarma, A Bhattacharyya… - …, 2021 - Springer
Alzheimer's disease (AD) is a major contributor of dementia leading to the degeneration of
neurons in the brain with major symptoms like loss of memory and learning. Many evidences …

The role and regulatory mechanism of hippo signaling components in the neuronal system

J Cheng, S Wang, Y Dong, Z Yuan - Frontiers in immunology, 2020 - frontiersin.org
The Hippo signaling pathway, an evolutionarily conserved protein kinase cascade, plays a
critical role in controlling organ size, cancer development, and tissue regeneration …

The Hippo signalling pathway and its implications in human health and diseases

M Fu, Y Hu, T Lan, KL Guan, T Luo… - Signal transduction and …, 2022 - nature.com
As an evolutionarily conserved signalling network, the Hippo pathway plays a crucial role in
the regulation of numerous biological processes. Thus, substantial efforts have been made …

Neuroinflammation pathways: a general review

T Shabab, R Khanabdali… - International Journal …, 2017 - Taylor & Francis
Activated microglial cells play an important role in immune and inflammatory responses in
central nervous system and neurodegenerative diseases. Many pro-apoptotic pathways are …

Neuroinflammation mechanisms and phytotherapeutic intervention: A systematic review

N Kaur, H Chugh, MK Sakharkar… - ACS chemical …, 2020 - ACS Publications
Neuroinflammation is indicated in the pathogenesis of several acute and chronic
neurological disorders. Acute lesions in the brain parenchyma induce intense and highly …

Neuroinflammation in Alzheimer's disease: current progress in molecular signaling and therapeutics

S Thakur, R Dhapola, P Sarma, B Medhi, DHK Reddy - Inflammation, 2023 - Springer
Alzheimer's disease, a neurodegenerative disease with amyloid beta accumulation as a
major hallmark, has become a dire global health concern as there is a lack of clear …

[HTML][HTML] An update on the role of Hippo signaling pathway in ischemia-associated central nervous system diseases

X Wei, G Huang, J Liu, J Ge, W Zhang, Z Mei - Biomedicine & …, 2023 - Elsevier
The most frequent reason of morbidity and mortality in the world, cerebral ischemia sets off a
chain of molecular and cellular pathologies that associated with some central nervous …

Inflammation and Alzheimer's disease: mechanisms and therapeutic implications by natural products

MA Rather, A Khan, S Alshahrani… - Mediators of …, 2021 - Wiley Online Library
Alzheimer's disease (AD) is a neurodegenerative disorder with no clear causative event
making the disease difficult to diagnose and treat. The pathological hallmarks of AD include …