[HTML][HTML] Evaluation of polymer nanoformulations in hepatoma therapy by established rodent models

Q Wang, P Zhang, Z Li, X Feng, C Lv, H Zhang… - Theranostics, 2019 - ncbi.nlm.nih.gov
Hepatoma is one of the most severe malignancies usually with poor prognosis, and many
patients are insensitive to the existing therapeutic agents, including the drugs for …

[HTML][HTML] Polymeric nanomedicines for the treatment of hepatic diseases

F Luo, Y Yu, M Li, Y Chen, P Zhang, C Xiao… - Journal of …, 2022 - Springer
The liver is an important organ in the human body and performs many functions, such as
digestion, detoxification, metabolism, immune responses, and vitamin and mineral storage …

Novel polymeric nanoparticles containing tanshinone IIA for the treatment of hepatoma

Q Li, Y Wang, N Feng, Z Fan, J Sun… - Journal of drug …, 2008 - Taylor & Francis
Novel polylactic acid nanoparticles containing tanshinone IIA (TS-PLA-NPs) were
synthesized by a single oil-in-water emulsion/solvent evaporation method. In this study, the …

New molecular targets for functionalized nanosized drug delivery systems in personalized therapy for hepatocellular carcinoma

C Turato, A Balasso, V Carloni, C Tiribelli… - Journal of Controlled …, 2017 - Elsevier
Hepatocellular carcinoma, the most frequent solid tumor of the liver, has a very poor
prognosis, being the second most common cause of death from cancer worldwide. The …

Heparosan as a potential alternative to hyaluronic acid for the design of biopolymer-based nanovectors for anticancer therapy

M Rippe, TF Stefanello, V Kaplum, EA Britta… - Biomaterials …, 2019 - pubs.rsc.org
Glycosaminoglycans (GAGs) are important components of the extracellular matrix that have
attracted great interest for drug delivery and pharmaceutical applications due to their diverse …

Generation of matched patient-derived xenograft in vitro-in vivo models using 3D macroporous hydrogels for the study of liver cancer

ELS Fong, TB Toh, QXX Lin, Z Liu, L Hooi… - Biomaterials, 2018 - Elsevier
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide, often
manifesting at the advanced stage when cure is no longer possible. The discrepancy …

Delivery of triptolide with reduction-sensitive polymer nanoparticles for liver cancer therapy on patient-derived xenografts models

M He, L Yu, Y Yang, B Zou, W Ma, M Yu, J Lu… - Chinese Chemical …, 2020 - Elsevier
Hepatocellular carcinoma (HCC) has become the fourth predominant cause of cancer-
related deaths worldwide, and HCC is still one of the worst prognoses for survival as it is …

Facile Fabrication of Nanoparticles with Dual-Targeting Ligands for Precise Hepatocellular Carcinoma Therapy In Vitro and In Vivo

Y Xiang, W Huang, C Huang, J Long… - Molecular …, 2020 - ACS Publications
Efficient hepatocellular carcinoma (HCC) therapy remains a significant challenge due to the
unsatisfactory targeting efficiency of nanoparticles (NPs) with either a passive targeting or a …

[HTML][HTML] Liver cancer: current and future trends using biomaterials

SA Chew, S Moscato, S George, B Azimi, S Danti - Cancers, 2019 - mdpi.com
Hepatocellular carcinoma (HCC) is the fifth most common type of cancer diagnosed and the
second leading cause of death worldwide. Despite advancement in current treatments for …

Nanomedicines: a theranostic approach for hepatocellular carcinoma

A Usmani, A Mishra, M Ahmad - Artificial cells, nanomedicine, and …, 2018 - Taylor & Francis
The liver is an imperative organ of tremendous importance concerned with maintenance of
metabolic functions and detoxification of exogenous and endogenous challenges like …