The microtubule cytoskeleton undergoes major reorganizations during mitosis, process
extension, and ciliogenesis. To achieve these rearrangements, cells must rapidly increase …

How cells regulate α-and β-tubulin to meet the demand for αβ-heterodimers and avoid
consequences of monomer imbalance is not understood. We investigate the role of gene …

Microtubule dynamics play essential roles in intracellular organization and cell division.
They result from structural and biochemical properties of αβ-tubulin heterodimers and how …

Microtubules are key cytoskeletal elements of all eukaryotic cells and are assembled of
evolutionarily conserved α-tubulin–β-tubulin heterodimers. Despite their uniform structure …

The microtubule cytoskeleton is assembled from the α-and β-tubulin subunits of the
canonical tubulin heterodimer, which polymerizes into microtubules, and a small number of …

Many effectors of microtubule assembly in vitro enhance the polymerization of subunits.
However, several Saccharomyces cerevisiae genes that affect cellular microtubule …

Microtubules are cytoskeletal filaments underlying the morphology and functions of all
eukaryotic cells. In higher eukaryotes, the basic building blocks of these non-covalent …

The microtubule cytoskeleton is assembled from a finite pool of α, β-tubulin, the size of which
is controlled by an autoregulation mechanism. Cells also tightly regulate the architecture …

Microtubules are dynamic cytoskeletal polymers that assemble from α/β-tubulin and are vital
for the establishment of cell polarity, vesicle trafficking and formation of the mitotic/meiotic …

Microtubules are dynamic cytoskeleton filaments that are essential for a wide range of
cellular processes. They are polymerized from tubulin, a heterodimer of α-and β-subunits …