Diversity and Mechanisms of Action of Plant, Animal, and Human Antimicrobial Peptides

G Satchanska, S Davidova, A Gergova - Antibiotics, 2024 - mdpi.com
Antimicrobial peptides (AMPs) are usually made up of fewer than 100 amino acid residues.
They are found in many living organisms and are an important factor in those organisms' …

Antimicrobial Peptides: Potential Alternative to Antibiotics and Overcoming Limitations for Future Therapeutic Applications

V Somase, SA Desai, VP Patel, V Patil… - International Journal of …, 2024 - Springer
Among all health-related issues, the rising concerns about drug resistance led to the look for
alternative pharmaceutical drugs that are effective against both infectious and noninfectious …

[HTML][HTML] Natural roles of antimicrobial peptides in microbes, plants and animals

G Maróti, A Kereszt, E Kondorosi, P Mergaert - Research in microbiology, 2011 - Elsevier
Antimicrobial peptides (AMPs) are ribosomally synthesized natural antibiotics that are
crucial effectors of innate immune systems in all living organisms. AMPs are diverse …

Antimicrobial peptides: Application informed by evolution

BP Lazzaro, M Zasloff, J Rolff - Science, 2020 - science.org
BACKGROUND Antimicrobial peptides (AMPs) are small proteins with potent antibacterial,
antiviral, and antifungal activity. AMPs are ubiquitous among multicellular eukaryotes, with …

Biological functions and applications of antimicrobial peptides

L Wang, L Qu, S Lin, Q Yang, X Zhang… - Current Protein and …, 2022 - ingentaconnect.com
Despite antimicrobial resistance, which is attributed to the misuse of broad-spectrum
antibiotics, antibiotics can indiscriminately kill pathogenic and beneficial microorganisms …

Antimicrobial peptides: new candidates in the fight against bacterial infections

O Toke - Peptide Science: Original Research on Biomolecules, 2005 - Wiley Online Library
Antimicrobial peptides (AMPs) of innate origin are agents of the most ancient form of
defense systems. They can be found in a wide variety of species ranging from bacteria …

Antimicrobial peptides: key components of the innate immune system

M Pasupuleti, A Schmidtchen… - Critical reviews in …, 2012 - Taylor & Francis
Life-threatening infectious diseases are on their way to cause a worldwide crisis, as treating
them effectively is becoming increasingly difficult due to the emergence of antibiotic resistant …

Mammalian antimicrobial peptides: promising therapeutic targets against infection and chronic inflammation

P Dutta, S Das - Current topics in medicinal chemistry, 2016 - ingentaconnect.com
Antimicrobial peptides (AMPs) are integral components of the host innate immune system
and functional throughout the plant and animal kingdoms. AMPs are short cationic …

Elucidating unusual modes of action and resistance of antibacterial peptides

L dos Santos Machado… - Current Topics in …, 2017 - ingentaconnect.com
The emergence of bacterial resistance to conventional antibiotics has been become a major
issue in the health system. Currently, studies are being performed to develop new drugs that …

Antimicrobial peptides: A new hope in biomedical and pharmaceutical fields

A Moretta, C Scieuzo, AM Petrone, R Salvia… - Frontiers in cellular …, 2021 - frontiersin.org
Antibiotics are essential drugs used to treat pathogenic bacteria, but their prolonged use
contributes to the development and spread of drug-resistant microorganisms. Antibiotic …