More than 20 matrix metalloproteinases (MMPs) and four of their endogenous tissue
inhibitors (TIMPs) act together to control tightly temporally restricted, focal proteolysis of …

The matrix metalloproteinase (MMP) family, comprising more than 20 isoforms, modulates
the extracellular milieu by degrading extracellular matrix (ECM) proteins. Because MMP is …

The brain changes in response to experience and altered environment. To do that, the
nervous system often remodels the structures of neuronal circuits. This structural plasticity of …

Matrix metalloproteinases (MMPs), together with their endogenous inhibitors (TIMPs) form
an enzymatic system that plays an important role in a variety of physiological and …

The matrix metalloproteinases (MMPs) are a family of zinc‐dependent extracellular
proteases that have been implicated in CNS development and disease. Crucial homeostatic …

Matrix metalloproteases (MMPs) and tissue inhibitors of metalloproteases (TIMPs) are
involved in many cell migration phenomena and produced by many cell types, including …

In neurodegenerative disease or after brain injury, parenchymal cells in the central nervous
system are activated to produce inflammatory mediators, mainly consisting of cytokine …

Matrix metalloproteinases (MMPs) are proteolytic enzymes that degrade the components of
the extracellular matrix (ECM). The balance between MMPs and their inhibitors [tissue …

Matrix metalloproteinases (MMPs) are implicated in the pathogenesis of inflammatory
disorders of the central nervous system (CNS) whereas the contribution of the major …

Matrix metalloproteinases (MMPs) have been implicated in several diseases of the nervous
system. Here we review the evidence that supports this idea and discuss the possible …