Drug resistance has been rapidly evolving with regard to the first-line malaria treatment,
artemisinin-based combination therapies. It has been an open question whether predictive …

Resistance to antimalarial drugs, and in particular to the artemisinin derivatives and their
partner drugs, threatens recent progress toward regional malaria elimination and eventual …

Malaria is a major global health challenge with 300 million new cases every year. The most
effective regimen for treating Plasmodium falciparum malaria is based on artemisinin and its …

Plasmodium falciparum, the malignant malaria parasite, has developed resistance to
artemisinin, the most important and widely used antimalarial drug at present. Currently …

For more than five decades, Southeast Asia (SEA) has been fertile ground for the
emergence of drug-resistant Plasmodium falciparum malaria. After generating parasites …

Due to their rapid, potent action on young and mature intraerythrocytic stages, artemisinin
derivatives are central to drug combination therapies for Plasmodium falciparum malaria …

Ensemble machine learning modeling for the prediction of artemisinin resistance in malaria -
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Background Plasmodium falciparum malaria is one of the most widespread parasitic
infections in humans and remains a leading global health concern. Malaria elimination …

Plasmodium falciparum, the causative agent of malaria, has been developing resistance to
several drugs worldwide for more than five decades. Initially, resistance was against drugs …

The emergence and spread of artemisinin resistant Plasmodium falciparum, first in the
Greater Mekong Subregion (GMS), and now in East Africa, is a major threat to global malaria …