DNA mismatch repair (MMR) corrects mismatched base pairs mainly caused by DNA
replication errors. The fundamental mechanisms and proteins involved in the early reactions …

▪ Abstract DNA mismatch repair (MMR) guards the integrity of the genome in virtually all
cells. It contributes about 1000-fold to the overall fidelity of replication and targets mispaired …

▪ Abstract Mismatch repair (MMR) systems play a central role in promoting genetic stability
by repairing DNA replication errors, inhibiting recombination between non-identical DNA …

DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role
in maintaining genomic stability. The specificity of MMR is primarily for base-base …

The genome of all organisms is constantly being challenged by endogenous and
exogenous sources of DNA damage. Errors like base: base mismatches or small insertions …

The molecular mechanisms of the DNA mismatch repair (MMR) system have been
uncovered over the last decade, especially in prokaryotes. The results obtained for …

▪ Abstract DNA mismatch repair (MMR) is an evolutionarily conserved process that corrects
mismatches generated during DNA replication and escape proofreading. MMR proteins also …

A considerable surge of interest in the mismatch repair (MMR) system has been brought
about by the discovery of a link between Lynch syndrome, an inherited predisposition to …

DNA mismatch repair (MMR) is an important DNA repair pathway that plays critical roles in
DNA replication fidelity, mutation avoidance and genome stability, all of which contribute …

The primary role of mismatch repair (MMR) is to maintain genomic stability by removing
replication errors from DNA. This repair pathway was originally implicated in human cancer …