[HTML][HTML] A quest for genetic causes underlying signaling pathways associated with neural tube defects

S Rai, L Leydier, S Sharma, J Katwala… - Frontiers in Pediatrics, 2023 - frontiersin.org
Neural tube defects are dreadful congenital deformities of the nervous system that occur
owing to failure of normal neural tube closure. Genetic and non-genetic factors contribute to …

Genetic basis of neural tube defects

AG Bassuk, Z Kibar - Seminars in pediatric neurology, 2009 - Elsevier
Neural tube defects (NTDs) represent a common group of severe congenital malformations
of the central nervous system. They result from failure of neural tube closure during early …

Current perspectives on the genetic causes of neural tube defects

P De Marco, E Merello, S Mascelli, V Capra - neurogenetics, 2006 - Springer
Neural tube defects (NTDs) are a group of severe congenital abnormalities resulting from
the failure of neurulation. The pattern of inheritance of these complex defects is …

Neural tube defects

NDE Greene, AJ Copp - Annual review of neuroscience, 2014 - annualreviews.org
Neural tube defects (NTDs), including spina bifida and anencephaly, are severe birth
defects of the central nervous system that originate during embryonic development when the …

Genetics of neural tube defects

J Gelineau-van Waes, RH Finnell - Seminars in Pediatric Neurology, 2001 - Elsevier
Neural tube defects (NTDs) are common congenital malformations that occur when the
embryonic neural tube fails to close properly during early development. Although …

Investigations into the etiology of neural tube defects

RM Cabrera, DS Hill, AJ Etheredge… - Birth Defects Research …, 2004 - Wiley Online Library
Neural tube defects (NTDs) are serious malformations affecting approximately 1 per 1000
births, yet the mechanisms by which they arise are unknown. There have been consistent …

Folate and epigenetic mechanisms in neural tube development and defects

SV Meethal, KJ Hogan, CS Mayanil, BJ Iskandar - Child's nervous system, 2013 - Springer
Introduction Multiple genetic and epigenetic factors involved in central nervous system
(CNS) development influence the incidence of neural tube defects (NTDs). Discussion The …

Toward understanding the genetic basis of neural tube defects

Z Kibar, V Capra, P Gros - Clinical genetics, 2007 - Wiley Online Library
Neural tube defects (NTDs) represent a common group of severe congenital malformations
that result from failure of neural tube closure during early development. Their etiology is …

Closing in on mechanisms of open neural tube defects

S Lee, JG Gleeson - Trends in neurosciences, 2020 - cell.com
Neural tube defects (NTDs) represent a failure of the neural plate to complete the
developmental transition to a neural tube. NTDs are the most common birth anomaly of the …

Human neural tube defects: genetic causes and prevention

P De Marco, E Merello, A Cama, Z Kibar, V Capra - Biofactors, 2011 - Wiley Online Library
Neural tube defects (NTDs) are severe congenital malformations affecting 1–2 in 1,000 live
births, whose etiology is multifactorial, involving environmental and genetic factors. NTDs …