How to use high-sensitivity cardiac troponins in acute cardiac care

K Thygesen, J Mair, E Giannitsis, C Mueller… - European heart …, 2012 - academic.oup.com
Recommendations for the use of cardiac troponin (cTn) measurement in acute cardiac care
have recently been published. 1 Subsequently, a high-sensitivity (hs) cTn T assay was …

How to interpret elevated cardiac troponin levels

VS Mahajan, P Jarolim - Circulation, 2011 - Am Heart Assoc
The National Academy of Clinical Biochemistry issued a guideline in 2007 that stated that “in
the presence of a clinical history suggestive of ACS, the following is considered indicative of …

What to do when you question cardiac troponin values

J Mair, B Lindahl, C Müller… - … heart journal: acute …, 2018 - journals.sagepub.com
High-sensitivity cardiac troponin assays enable cardiac troponin measurement with a high
degree of analytical sensitivity and a low level of analytical imprecision at the low measuring …

A new season for cardiac troponin assays: it's time to keep a scorecard

FS Apple - Clinical chemistry, 2009 - academic.oup.com
Advancements in cardiac troponin (cTn) 2 assay technology have created a conundrum for
clinicians and laboratory scientists, who must determine which assays are best for optimal …

High-sensitivity troponin in the evaluation of patients with suspected acute coronary syndrome: a stepped-wedge, cluster-randomised controlled trial

ASV Shah, A Anand, FE Strachan, AV Ferry, KK Lee… - The Lancet, 2018 - thelancet.com
Background High-sensitivity cardiac troponin assays permit use of lower thresholds for the
diagnosis of myocardial infarction, but whether this improves clinical outcomes is unknown …

Clinical use of high-sensitivity cardiac troponin in patients with suspected myocardial infarction

R Twerenbold, J Boeddinghaus, T Nestelberger… - Journal of the American …, 2017 - jacc.org
High-sensitivity cardiac troponin (hs-cTn) assays have been used clinically by thousands of
physicians in many countries throughout the world since their clinical introduction 7 years …

Cardiac troponin elevations in patients without acute coronary syndrome

CW Hamm, E Giannitsis, HA Katus - Circulation, 2002 - Am Heart Assoc
Cardiac troponin T and troponin I are the most specific and sensitive laboratory markers of
myocardial cell injury and therefore have replaced creatine kinase MB as the gold standard …

Consequences of implementing a cardiac troponin assay with improved sensitivity at Swedish coronary care units: an analysis from the SWEDEHEART registry

KM Eggers, B Lindahl, D Melki… - European heart …, 2016 - academic.oup.com
Aims Cardiac troponin (cTn) assays with improved sensitivity are increasingly utilized for the
assessment of patients admitted because of suspected acute coronary syndrome (ACS) …

Single high-sensitivity cardiac troponin I to rule out acute myocardial infarction

Y Sandoval, SW Smith, SA Love, A Sexter… - The American Journal of …, 2017 - Elsevier
Background This study examined the performance of single high-sensitivity cardiac troponin
I (hs-cTnI) measurement strategies to rule out acute myocardial infarction. Methods This was …

Combining high-sensitivity cardiac troponin I and cardiac troponin T in the early diagnosis of acute myocardial infarction

N van der Linden, K Wildi, R Twerenbold… - Circulation, 2018 - Am Heart Assoc
Background: Combining 2 signals of cardiomyocyte injury, cardiac troponin I (cTnI) and T
(cTnT), might overcome some individual pathophysiological and analytical limitations and …