Controlling shear stress in 3D bioprinting is a key factor to balance printing resolution and stem cell integrity

A Blaeser, DF Duarte Campos, U Puster… - Advanced …, 2016 - Wiley Online Library
DOI: 10.1002/adhm. 201500677 in cell biology,[29, 30] eg, in cell signaling and protein
expression.[31–33] For instance, it is reported that shear stress promotes maturation of …

[PDF][PDF] Dual-stage crosslinking of a gel-phase bioink improves cell viability and homogeneity for 3D bioprinting

K Dubbin, Y Hori, KK Lewis, SC Heilshorn - Adv. Healthc. Mater, 2016 - stanford.edu
DOI: 10.1002/adhm. 201600636 extensional forces during extrusion, resulting in cell
membrane damage and death.[9, 10] Third, viscous fluids are typically printed and …

Cell encapsulation in gelatin bioink impairs 3D bioprinting resolution

R Schwartz, M Malpica, GL Thompson… - Journal of the mechanical …, 2020 - Elsevier
Recent advances in three-dimensional (3D) bioprinting technologies have enabled precise
patterning of cellular components along with biomimetic constructs for tissue engineering …

Characterization of cell damage and proliferative ability during and after bioprinting

L Ning, N Betancourt, DJ Schreyer… - … Biomaterials Science & …, 2018 - ACS Publications
When a biomaterial solution containing living cells is subject to bioprinting, the cells
experience process-induced stresses, including shear and extensional stresses. These …

Microfluidic bioprinting of heterogeneous 3D tissue constructs using low‐viscosity bioink

C Colosi, SR Shin, V Manoharan, S Massa… - Advanced …, 2016 - Wiley Online Library
DOI: 10.1002/adma. 201503310 scaffold support. In the past, researchers have tried to
employ different technologies for deposition and patterning of bioinks in 3D printing such as …

Volumetric printing across melt electrowritten scaffolds fabricates multi‐material living constructs with tunable architecture and mechanics

G Größbacher, M Bartolf‐Kopp, C Gergely… - Advanced …, 2023 - Wiley Online Library
Major challenges in biofabrication revolve around capturing the complex, hierarchical
composition of native tissues. However, individual 3D printing techniques have limited …

Hydrogel bioink reinforcement for additive manufacturing: a focused review of emerging strategies

D Chimene, R Kaunas, AK Gaharwar - Advanced materials, 2020 - Wiley Online Library
Bioprinting is an emerging approach for fabricating cell‐laden 3D scaffolds via robotic
deposition of cells and biomaterials into custom shapes and patterns to replicate complex …

Rheological analysis of bio-ink for 3D bio-printing processes

MA Habib, B Khoda - Journal of manufacturing processes, 2022 - Elsevier
Abstract 3D bio-printing is an emerging technology to fabricate tissue scaffold in-vitro
through the controlled allocation of biomaterial and cells, which can mimic the in-vivo …

Accurate calibration in multi-material 3D bioprinting for tissue engineering

E Sodupe-Ortega, A Sanz-Garcia, A Pernia-Espinoza… - Materials, 2018 - mdpi.com
Most of the studies in three-dimensional (3D) bioprinting have been traditionally based on
printing a single bioink. Addressing the complexity of organ and tissue engineering …

[PDF][PDF] 3D bioprinting of vascularized, heterogeneous cell‐laden tissue constructs

DB Kolesky, RL Truby, AS Gladman… - Advanced …, 2014 - scholar.harvard.edu
DOI: 10.1002/adma. 201305506 multiple materials in 3D (Scheme 1). Hence, we first
implemented a custom-designed, large-area 3D bioprinter with four independently …