Transformation of colitis and colorectal cancer: a tale of gut microbiota

K Xia, R Gao, L Li, X Wu, T Wu, Y Ruan… - Critical Reviews in …, 2023 - Taylor & Francis
Intestinal inflammation modifies host physiology to promote the occurrence of colorectal
cancer (CRC), as seen in colitis-associated CRC. Gut microbiota is crucial in cancer …

Microbiome and colorectal cancer: Unraveling host-microbiota interactions in colitis-associated colorectal cancer development

M Kang, A Martin - Seminars in immunology, 2017 - Elsevier
Dysbiosis of gut microbiota occurs in many human chronic immune-mediated diseases,
such as inflammatory bowel disease (IBD) and colitis-associated colorectal cancer (CAC) …

Role of gut microbiota in the development and treatment of colorectal cancer

C Lin, X Cai, J Zhang, W Wang, Q Sheng, H Hua… - Digestion, 1963 - karger.com
Human guts harbor abundant microbes that regulate many aspects of host physiology.
However, bacterial imbalance or dysbiosis in the gut due to the dietary or environmental …

Gut microbiota and colorectal cancer: insights into pathogenesis for novel therapeutic strategies

Y Kang, W Pan, Y Cai - Zeitschrift für Gastroenterologie, 2017 - thieme-connect.com
Colorectal cancer (CRC), as a leading cause of cancer-related death, is triggered by the
complex interplay of host genetics and environmental factors. Mounting evidence has shed …

Interaction between microbiota and immunity and its implication in colorectal cancer

C Xing, Y Du, T Duan, K Nim, J Chu, HY Wang… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is one of the leading causes of cancer-related death in the world.
Besides genetic causes, colonic inflammation is one of the major risk factors for CRC …

Factors determining colorectal cancer: the role of the intestinal microbiota

E Nistal, N Fernández-Fernández, S Vivas… - Frontiers in …, 2015 - frontiersin.org
The gastrointestinal tract, in particular the colon, holds a complex community of
microorganisms, which are essential for maintaining homeostasis. However, in recent years …

Dysbiosis of gut microbiota in promoting the development of colorectal cancer

S Zou, L Fang, MH Lee - Gastroenterology report, 2018 - academic.oup.com
Gastrointestinal microbiome, containing at least 100 trillion bacteria, resides in the mucosal
surface of human intestine. Recent studies show that perturbations in the microbiota may …

Gut microbiota and probiotics in colon tumorigenesis

Y Zhu, TM Luo, C Jobin, HA Young - Cancer letters, 2011 - Elsevier
The human gastrointestinal tract harbors a complex and abundant microbial community
reaching as high as 1013–1014 microorganisms in the colon. This endogenous microbiota …

[HTML][HTML] Inflammation and colorectal cancer, when microbiota-host mutualism breaks

M Candela, S Turroni, E Biagi… - World journal of …, 2014 - ncbi.nlm.nih.gov
Structural changes in the gut microbial community have been shown to accompany the
progressive development of colorectal cancer. In this review we discuss recent hypotheses …

The intestinal microbiota and colorectal cancer

Y Cheng, Z Ling, L Li - Frontiers in immunology, 2020 - frontiersin.org
The intestinal microbiota, composed of a large population of microorganisms, is often
considered a “forgotten organ” in human health and diseases. Increasing evidence indicates …