A pilot study to determine the safety and feasibility of oropharyngeal administration of own mother's colostrum to extremely low-birth-weight infants

NA Rodriguez, PP Meier, MW Groer… - … in neonatal care, 2010 - journals.lww.com
Own mother's colostrum is rich in cytokines and other immune agents that may stimulate
oropharyngeal-associated lymphoid tissue if administered oropharyngeally to extremely low …

[PDF][PDF] A randomized controlled trial of the oropharyngeal administration of mother's colostrum to extremely low birth weight infants in the first days of life

NA Rodriguez, MW Groer, JM Zeller… - Neonatal Intensive …, 2011 - researchgate.net
Background: Own mother's colostrum (OMC) provides immune protection to extremely low
birth weight (ELBW) infants in the immediate post-birth period, however clinical instability …

Oropharyngeal administration of colostrum to extremely low birth weight infants: theoretical perspectives

NA Rodriguez, PP Meier, MW Groer, JM Zeller - Journal of Perinatology, 2009 - nature.com
Studies in adults have shown that the oropharyngeal route can be used to effectively and
safely administer interferon-α, an immune cell-derived cytokine, to patients who are unable …

Oropharyngeal colostrum administration in very low birth weight infants: a randomized controlled trial

Y Zhang, F Ji, X Hu, Y Cao… - Pediatric Critical Care …, 2017 - journals.lww.com
Objectives: Studies have confirmed the safety of oropharyngeal administration of colostrum
in very low birth weight infants. However, the effect of oropharyngeal administration of …

Oropharyngeal colostrum administration in extremely premature infants: an RCT

J Lee, HS Kim, YH Jung, KY Choi, SH Shin… - …, 2015 - publications.aap.org
OBJECTIVE: To determine the immunologic effects of oropharyngeal colostrum
administration in extremely premature infants. METHODS: We conducted a double-blind …

Randomized controlled trial of oropharyngeal colostrum administration in very‐low‐birth‐weight preterm infants

DMLM Ferreira, AMM Oliveira… - Journal of pediatric …, 2019 - Wiley Online Library
Objective: The purpose of this study was to evaluate the effects of oropharyngeal colostrum
administration in the incidence of late‐onset clinical and proven sepsis and in …

[HTML][HTML] Early provision of oropharyngeal colostrum leads to sustained breast milk feedings in preterm infants

R Snyder, A Herdt, N Mejias-Cepeda, J Ladino… - Pediatrics & …, 2017 - Elsevier
Background Oropharyngeal colostrum (OC) application strategies have been shown to be
feasible and safe for very low birth weight (VLBW) infants. Evidence to support the nutritional …

Colostrum as oral immune therapy to promote neonatal health

SM Gephart, M Weller - Advances in Neonatal Care, 2014 - journals.lww.com
It is well known that the immune response is blunted and underdeveloped in the premature
infant, but human milk supports the infant's growth, function, and effectiveness. Thus, own …

Early administration of oropharyngeal colostrum to extremely low birth weight infants

JK Seigel, PB Smith, PL Ashley, CM Cotten… - Breastfeeding …, 2013 - liebertpub.com
Background: Human milk reduces morbidities in extremely low birth weight (ELBW) infants.
However, clinical instability often precludes ELBW infants from receiving early enteral feeds …

Enhancement of immune response mediated by oropharyngeal colostrum administration in preterm neonates

J Moreno‐Fernandez… - Pediatric Allergy and …, 2019 - Wiley Online Library
Background The immune system of preterm infants is immature, being a significant cause of
morbidity and mortality, particularly in the preterm infant. Oropharyngeal colostrum …