Systemic sclerosis is an autoimmune disease characterized by excessive dermal fibrosis
with progression to internal organs, vascular impairment and immune dysregulation …

Systemic sclerosis (SSc) is an autoimmune connective tissue disease that is characterized
by vasculopathy and excessive deposition of extracellular matrix, which causes fibrosis of …

Objective SSc is a connective tissue disease with multisystem disorder induced by the
inflammation and fibrosis following T and B cell abnormalities. Follicular helper CD4+ T …

Multiple Sclerosis (MS) is a chronic, inflammatory and neurodegenerative disease which
results from the destruction of myelin and associated collateral tissue damage within the …

SSc is an autoimmune disease characterized by inflammation and extracellular matrix
deposition that ultimately leads to loss of organ function. T cells appear to play a prominent …

Systemic sclerosis (SSc) is a progressive and highly debilitating autoimmune disorder
characterized by inflammation, fibrosis, and vascular damage of the connective tissue. T cell …

Follicular helper T (TFH) cells are essential for B-cell maturation and immunoglobulin
production after immunization with thymus-dependent antigens. Nevertheless, the …

Objectives Systemic sclerosis (SSc) is an autoimmune disease characterised by widespread
fibrosis, microangiopathy and autoantibodies. Follicular helper T (Tfh) cells CD4+ CXCR5+ …

Systemic sclerosis (SSc) is characterized by autoimmunity and tissue fibrosis. There is a
close association between specific autoantibodies and clinical features in patients with SSc …

Despite long-standing recognition of the importance of T cells in systemic sclerosis (SSc;
scleroderma), the role of CD8+ T cells in disease pathogenesis has not been well studied …