Nuclear pore complexes (NPCs) are composed of several copies of∼ 30 different proteins
called nucleoporins (Nups). NPCs penetrate the nuclear envelope (NE) and regulate the …

Nuclear pore complex (NPC)-mediated nucleocytoplasmic trafficking is essential for key
cellular processes, such as cell growth, cell differentiation, and gene regulation. The NPC …

Eukaryotic cell function depends on the physical separation of nucleoplasmic and
cytoplasmic components by the nuclear envelope (NE). Molecular communication between …

Nuclear pore complexes (NPCs) are canonically known to regulate nucleocytoplasmic
transport. However, research efforts over the last decade have demonstrated that NPCs and …

As the gatekeepers of the eukaryotic cell nucleus, nuclear pore complexes (NPCs) mediate
all molecular trafficking between the nucleoplasm and the cytoplasm. In recent years …

Nuclear‐pore complexes (NPCs) are large protein channels that span the nuclear envelope
(NE), which is a double membrane that encloses the nuclear genome of eukaryotes. Each of …

Nuclear pore complexes (NPCs) mediate transport across the nuclear envelope. In yeast,
they also interact with active genes, attracting or retaining them at the nuclear periphery. In …

Nuclear pore complexes (NPCs) are multiprotein aqueous channels that penetrate the
nuclear envelope connecting the nucleus and the cytoplasm. NPCs consist of multiple …

The gene gating hypothesis put forth by Blobel in 1985 was an alluring proposal outlining
functions for the nuclear pore complex (NPC) in transcription and nuclear architecture. Over …

In addition to their established roles in nucleocytoplasmic transport, the intimate association
of nuclear pore complexes (NPCs) with chromatin has long led to speculation that these …